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MIRAGE
proteolipid protein 1
Summary
- Gene Symbol
-
- PLP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Hereditary spastic paraplegia
- Leukodystrophy
- Palmitate
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| P60201 |
|
| A0A0S2Z4D4 |
|
| A8K9L3 |
|
| B4DI30 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| inflammatory response | ||
| chemical synaptic transmission | ||
| axon ensheathment | ||
| positive regulation of gene expression | ||
| astrocyte development |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| integrin alphav-beta3 complex | ||
| myelin sheath | ||
| synapse |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| structural molecule activity | ||
| protein binding | ||
| structural constituent of myelin sheath | ||
| identical protein binding | ||
| protein-containing complex binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- neuronal membrane glycoprotein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| neuron projection development |
| InterPro |
|---|
| Myelin proteolipid protein PLP, conserved site |
| Myelin proteolipid protein PLP |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110773 | hereditary spastic paraplegia 2 | |
| DOID:3210 | Pelizaeus-Merzbacher disease |
