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Guidelines

MIRAGE

phospholipid transfer protein

Summary

Gene Symbol

PLTP

Organism

Homo sapiens (human)

External Links

NCBI Gene

5360

KEGG Gene ID

PubChem

5360

Alliance of Genome Resources

HGNC:9093

Annotation

Keyword

Alternative splicing
Direct protein sequencing
Disulfide bond
Glycoprotein
Lipid transport
Nucleus
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P55058	Lipid transfer protein II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
lipid metabolic process	TAS
lipid transport	IDA
vitamin E biosynthetic process
positive regulation of cholesterol efflux	IDA
phospholipid transport	IDA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

cilium movement [inference]

cilium movement involved in cell motility [inference]

flagellated sperm motility

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

vitamin E metabolic process [inference]

vitamin E biosynthetic process

primary metabolic process [inference]

lipid metabolic process

small molecule metabolic process [inference]

vitamin metabolic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

fat-soluble vitamin biosynthetic process [inference]

vitamin E biosynthetic process

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility [inference]

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-containing complex remodeling [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

protein-lipid complex organization [inference]

protein-lipid complex remodeling [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

membrane organization [inference]

intermembrane lipid transfer

reproductive process [inference]

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

plasma lipoprotein particle organization [inference]

plasma lipoprotein particle remodeling [inference]

high-density lipoprotein particle remodeling

localization [inference]

establishment of localization [inference]

transport [inference]

lipid transport

organophosphate ester transport [inference]

phospholipid transport

organic hydroxy compound transport [inference]

sterol transport

nitrogen compound transport [inference]

ceramide transport

carbohydrate derivative transport [inference]

glycolipid transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of lipid localization [inference]

regulation of lipid transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of sterol transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

regulation of cholesterol transport [inference]

regulation of cholesterol efflux [inference]

positive regulation of cholesterol efflux

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of biological process [inference]

positive regulation of transport [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

positive regulation of lipid localization [inference]

positive regulation of lipid transport [inference]

positive regulation of sterol transport [inference]

positive regulation of cholesterol transport [inference]

positive regulation of cholesterol efflux

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular region	IDA
extracellular region	IBA
extracellular region	IEA
extracellular region	HDA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

extracellular protein-containing complex [inference]

plasma lipoprotein particle [inference]

high-density lipoprotein particle

cellular anatomical structure [inference]

extracellular region

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **16 - 20** of 31 in total

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GO Term	Evidence Code	PMID
ceramide transfer activity	IBA
phosphatidylcholine transfer activity	IDA
phosphatidylcholine transfer activity	IEA
cholesterol transfer activity	ISS
cholesterol transfer activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transfer activity [inference]

phosphatidylinositol transfer activity

glycolipid transfer activity [inference]

cerebroside transfer activity

phospholipid transfer activity

sterol transfer activity [inference]

cholesterol transfer activity

sphingolipid transfer activity [inference]

ceramide transfer activity

cerebroside transfer activity

sphingomyelin transfer activity

diacylglyceride transfer activity

binding [inference]

protein binding

very-low-density lipoprotein particle binding

phospholipid binding [inference]

diacylglycerol binding

sphingolipid binding [inference]

ceramide binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

cation binding [inference]

phosphatidylcholine binding

quaternary ammonium group binding [inference]

phosphatidylcholine binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding [inference]

molecular carrier activity [inference]

lipid carrier activity [inference]

lipid transfer activity [inference]

phosphatidylinositol transfer activity

glycolipid transfer activity [inference]

cerebroside transfer activity

phospholipid transfer activity

sterol transfer activity [inference]

cholesterol transfer activity

sphingolipid transfer activity [inference]

ceramide transfer activity

cerebroside transfer activity

sphingomyelin transfer activity

diacylglyceride transfer activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	18830	MGI:103151

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026