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sodium voltage-gated channel beta subunit 4

Summary

Gene Symbol

SCN4B

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 538100
PubChem: 538100

Annotation

Keyword

Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Reference proteome
Signal
Sodium channel
Transmembrane helix
Voltage-gated channel

Proteins

Displaying 1 entry
UniProt	Protein Name
Q08E08

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
neuronal action potential
regulation of ventricular cardiac muscle cell membrane repolarization	IEA	30032202
cardiac muscle cell action potential involved in contraction	IEA	30032202
regulation of sodium ion transmembrane transporter activity	IEA	30032202

GO Hierarchy

biological process

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport [inference]

regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport [inference]

regulation of sodium ion transmembrane transport [inference]

regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport [inference]

regulation of sodium ion transmembrane transporter activity

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of sodium ion transmembrane transporter activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of sodium ion transmembrane transport [inference]

regulation of sodium ion transmembrane transporter activity

regulation of membrane repolarization [inference]

regulation of cardiac muscle cell membrane repolarization [inference]

regulation of ventricular cardiac muscle cell membrane repolarization

regulation of biological quality [inference]

regulation of membrane potential [inference]

action potential [inference]

neuronal action potential

cardiac muscle cell action potential [inference]

cardiac muscle cell action potential involved in contraction

regulation of membrane repolarization [inference]

regulation of cardiac muscle cell membrane repolarization [inference]

regulation of ventricular cardiac muscle cell membrane repolarization

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of sodium ion transmembrane transporter activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
voltage-gated sodium channel complex	IEA	30032202
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated sodium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

sodium channel complex [inference]

voltage-gated sodium channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
sodium channel activity
sodium channel regulator activity	IEA	30032202
transmembrane transporter binding	IEA	30032202

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

sodium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

sodium channel activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity [inference]

sodium channel activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity

binding [inference]

protein binding [inference]

transmembrane transporter binding

molecular function regulator activity [inference]

transporter regulator activity [inference]

channel regulator activity [inference]

ion channel regulator activity [inference]

sodium channel regulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sodium channel subunit beta-4

Functional Category

C: Energy production and conversion
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cardiac muscle cell action potential involved in contraction
regulation of ventricular cardiac muscle cell membrane repolarization
sodium channel regulator activity
transmembrane transporter binding

Displaying **all 6** entries
InterPro
Immunoglobulin V-set domain
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Myelin P0 protein-related

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	6330	HUMAN09635
Rattus norvegicus	315611	RATNO39731
Mus musculus	399548	MOUSE62975
Danio rerio	566069	DANRE09090
Danio rerio	567239	DANRE36462
Pan troglodytes	742047	PANTR04451
Monodelphis domestica	100031519	MONDO24906
Equus caballus	100071197	HORSE39218
Callithrix jacchus	100398497	CALJA03549
Nomascus leucogenys	100579635	NOMLE10512