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phosphoglycolate phosphatase

Summary

Gene Symbol

PGP

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 538173
KEGG Gene ID: bta:538173
PubChem: 538173

Annotation

Keyword

Carbohydrate metabolism
Magnesium
Metal-binding
Protein phosphatase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q2T9S4	Aspartate-based ubiquitous Mg(2+)-dependent phosphatase Phosphoglycolate phosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glycerol biosynthetic process
negative regulation of gluconeogenesis
glycerophospholipid metabolic process

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process [inference]

glycerol biosynthetic process

alditol biosynthetic process [inference]

glycerol biosynthetic process

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

alcohol biosynthetic process [inference]

polyol biosynthetic process [inference]

alditol biosynthetic process [inference]

glycerol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of small molecule metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

regulation of glucose metabolic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

regulation of carbohydrate biosynthetic process [inference]

regulation of gluconeogenesis [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of carbohydrate metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of small molecule metabolic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

regulation of cellular biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of gluconeogenesis

Displaying 1 entry
GO Term	Evidence Code	PMID
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity
phosphoglycolate phosphatase activity
glycerol-3-phosphatase activity	IEA	30032202
magnesium ion binding
ADP phosphatase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

glycerol-1-phosphatase activity

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

nucleoside diphosphate phosphatase activity [inference]

ADP phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatase

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
hydrolase activity
metal ion binding
phosphoglycolate phosphatase activity

Displaying **all 4** entries
InterPro
2-phosphoglycolate phosphatase, eukaryotic
HAD superfamily
HAD-like superfamily
HAD-superfamily hydrolase, subfamily IIA

KEGG BRITE Database

Orthology

K19269

Name

phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]

References

17478634

Rhea

H₂O

phosphate

Enzyme

3.1.3.48

PMID

H₂O + sn-glycerol 3-phosphate

glycerol + phosphate

Enzyme

3.1.3.21

H₂O + sn-glycerol 1-phosphate

glycerol + phosphate

Enzyme

3.1.3.21

PMID

Ortholog

Displaying entries **41 - 50** of 80 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Aotus nancymaae	105709680			AOTNA20863
Propithecus coquereli	105813067			PROCO03448
Equus asinus asinus	106836277			EQUAS28128
Sinocyclocheilus grahami	107584220			SINGR13480
Sinocyclocheilus grahami	107594223			SINGR54491
Pan troglodytes	107966141			PANTR11488
Ictalurus punctatus	108274162			ICTPU05186
Crocodylus porosus	109314795			CROPO22942
Bos indicus	109578506	9915_0:0042c6
Phascolarctos cinereus	110221946			PHACI07340

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Last updated: December 9, 2024