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tubulin, alpha 8

Summary

Gene Symbol

Tuba8

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

53857

PubChem

53857

Alliance of Genome Resources

MGI:1858225

Annotation

Keyword

Cytoskeleton
GTP-binding
Hydrolase
Magnesium
Metal-binding
Microtubule
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JJZ2	Alpha-tubulin 8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	TAS	10772959
microtubule cytoskeleton organization	IBA
mitotic cell cycle	IBA
spermatogenesis	IMP	21041996
spermatid development	IMP	21041996

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

cell cycle [inference]

mitotic cell cycle

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

spermatid development

cellular developmental process [inference]

cell development [inference]

germ cell development [inference]

spermatid development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

spermatid development

spermatogenesis

cellular process involved in reproduction in multicellular organism [inference]

germ cell development [inference]

spermatid development

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

spermatid development

spermatogenesis

anatomical structure development [inference]

cell development [inference]

germ cell development [inference]

spermatid development

cellular developmental process [inference]

cell development [inference]

germ cell development [inference]

spermatid development

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle	IMP	21041996
cytoplasm	IMP	21041996
cytoplasm	IBA
microtubule	TAS	10772959
microtubule	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
structural constituent of cytoskeleton	TAS	10772959
structural constituent of cytoskeleton	IBA
GTP binding	IBA
GTP binding	IEA
hydrolase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

structural molecule activity [inference]

structural constituent of cytoskeleton

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
GTP binding
cytoskeleton organization
microtubule cytoskeleton organization
microtubule-based process
nucleotide binding
structural constituent of cytoskeleton

Displaying **all 9** entries
InterPro
Beta tubulin
Tubulin, C-terminal
Tubulin, conserved site
Tubulin/FtsZ, 2-layer sandwich domain
Tubulin/FtsZ, C-terminal
Tubulin/FtsZ, GTPase domain superfamily
Tubulin/FtsZ, GTPase domain
Tubulin/FtsZ-like, C-terminal domain
Tubulin

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	7277	SGD:S000004593
Saccharomyces cerevisiae S288C	7846	SGD:S000004593
Saccharomyces cerevisiae S288C	10376	SGD:S000004593
Saccharomyces cerevisiae S288C	22142	SGD:S000004593
Saccharomyces cerevisiae S288C	22143	SGD:S000004593
Saccharomyces cerevisiae S288C	22144	SGD:S000004593
Saccharomyces cerevisiae S288C	22145	SGD:S000004593
Saccharomyces cerevisiae S288C	22146	SGD:S000004593
Saccharomyces cerevisiae S288C	22147	SGD:S000004593
Homo sapiens	51807		HUMAN59124