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thromboxane A2 receptor

Summary

Gene Symbol

TBXA2R

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 538783
PubChem: 538783

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q95125	Prostanoid TP receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
positive regulation of vasoconstriction	IEA	30032202
positive regulation of blood pressure	IEA	30032202
inflammatory response	IEA	30032202
positive regulation of cytosolic calcium ion concentration	IEA	30032202
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

regulation of blood pressure [inference]

positive regulation of blood pressure

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

positive regulation of vasoconstriction

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
thromboxane A2 receptor activity	IEA	30032202
thromboxane receptor activity

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

thromboxane receptor activity

thromboxane A2 receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

thromboxane a2 receptor

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
inflammatory response
positive regulation of blood pressure
positive regulation of cytosolic calcium ion concentration
positive regulation of vasoconstriction
thromboxane receptor activity

Displaying **all 4** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor
Thromboxane receptor

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	6915	HUMAN39757
Mus musculus	21390	MOUSE02936
Rattus norvegicus	24816	RATNO37728
Pan troglodytes	468667	PANTR16775
Canis lupus familiaris	485056	CANLF08035
Macaca mulatta	721732	MACMU20054
Monodelphis domestica	100010675	MONDO18744
Ornithorhynchus anatinus	100090815	ORNAN30391
Taeniopygia guttata	100231011	TAEGU15934
Pongo abelii	100433359	PONAB15951