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ATPase copper transporting beta

Summary

Gene Symbol

ATP7B

Organism

Homo sapiens (human)

External Links

NCBI Gene

540

PubChem

540

Alliance of Genome Resources

HGNC:870

JoGo

ATP7B

TogoVar

ATP7B

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Copper transport
Cytoplasm
Disease variant
Endosome
Golgi apparatus
Magnesium
Metal-binding
Mitochondrion
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Ribosomal frameshifting
Translocase
Transmembrane helix

Proteins

Displaying **all 9** entries
UniProt	Protein Name
A0AAQ5BGL6	Copper pump 2
B7ZLR3	Copper pump 2
B7ZLR4	Copper pump 2
A0A669KB88	Copper pump 2
P35670	Copper pump 2 Wilson disease-associated protein
F5H562
E7ET55	Copper pump 2
F5H748	Copper pump 2
A0AAQ5BGP2	Copper pump 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
copper ion transport	IDA	26004889
copper ion transport	IMP	9837819
copper ion transport	IGI	12572677 26004889
intracellular copper ion homeostasis	TAS	16554302
intracellular copper ion homeostasis	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation

protein maturation by copper ion transfer

primary metabolic process [inference]

protein metabolic process [inference]

protein maturation

protein maturation by copper ion transfer

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein maturation

protein maturation by copper ion transfer

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein maturation

protein maturation by copper ion transfer

cellular process [inference]

maintenance of location in cell [inference]

sequestering of calcium ion

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

copper ion export

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

copper ion export

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

viral process [inference]

viral translational frameshifting

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

copper ion homeostasis [inference]

intracellular copper ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

intracellular zinc ion homeostasis

copper ion homeostasis [inference]

intracellular copper ion homeostasis

response to stimulus [inference]

response to chemical [inference]

response to inorganic substance [inference]

response to metal ion [inference]

response to copper ion

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

copper ion transport

copper ion import

copper ion transmembrane transport [inference]

copper ion export

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

copper ion export

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

copper ion export

xenobiotic transport [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

secretion [inference]

body fluid secretion [inference]

lactation

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

copper ion export

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

copper ion transmembrane transport [inference]

copper ion export

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export from cell [inference]

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

establishment of localization in cell

maintenance of location [inference]

maintenance of location in cell [inference]

sequestering of calcium ion

biological regulation [inference]

regulation of biological quality [inference]

regulation of body fluid levels [inference]

body fluid secretion [inference]

lactation

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS
mitochondrion	HTP	34800366
late endosome	IDA	15681833
Golgi apparatus	IDA
trans-Golgi network	IDA	15269005 16472602

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

trans-Golgi network membrane

bounding membrane of organelle [inference]

Golgi membrane

plasma membrane region [inference]

basolateral plasma membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

endosome [inference]

late endosome

perinuclear region of cytoplasm

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
ATP hydrolysis activity	IEA
P-type divalent copper transporter activity	NAS	12763797
P-type divalent copper transporter activity	TAS	16472602
P-type divalent copper transporter activity	IMP	9837819
P-type divalent copper transporter activity	IBA