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CD320 antigen

Summary

Gene Symbol

Cd320

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

54219

PubChem

54219

Alliance of Genome Resources

MGI:1860083

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Growth factor
Metal-binding
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Z1P5	Transcobalamin receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
receptor-mediated endocytosis involved in cholesterol transport	IBA
cobalamin transport	IMP ISO ISS	23430977
regulation of vitamin metabolic process	IMP	23430977
vesicle-mediated transport	IEA
positive regulation of B cell proliferation	ISO ISS

GO Hierarchy

biological process

immune system process [inference]

lymphocyte costimulation [inference]

B cell costimulation

cellular process [inference]

signal transduction

vesicle-mediated transport

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis involved in cholesterol transport

cellular localization [inference]

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis involved in cholesterol transport

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

vitamin transport [inference]

cobalamin transport

organic substance transport [inference]

cobalamin transport

nitrogen compound transport [inference]

cobalamin transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis involved in cholesterol transport

establishment of localization in cell [inference]

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

cellular localization [inference]

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of metabolic process [inference]

regulation of small molecule metabolic process [inference]

regulation of vitamin metabolic process

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of cellular process [inference]

signal transduction

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

regulation of B cell activation [inference]

regulation of B cell proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

lymphocyte costimulation [inference]

B cell costimulation

positive regulation of lymphocyte proliferation [inference]

positive regulation of B cell proliferation

positive regulation of B cell activation [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
early endosome	IBA
plasma membrane	IBA IMP ISO ISS	23430977
endoplasmic reticulum	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

early endosome

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
growth factor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity [inference]

growth factor activity

small molecule binding [inference]

vitamin binding [inference]

cobalamin binding

heterocyclic compound binding [inference]

cobalamin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding

organic cyclic compound binding [inference]

tetrapyrrole binding [inference]

cobalamin binding

cargo receptor activity

lipoprotein particle receptor activity [inference]

low-density lipoprotein particle receptor activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

CD320 antigen

Functional Category

C: Energy production and conversion
G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
InterPro
LDL receptor-like superfamily
Low-density lipoprotein (LDL) receptor class A repeat
Low-density lipoprotein (LDL) receptor class A, conserved site

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060741	methylmalonic acidemia due to transcobalamin receptor defect	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 70 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Pan paniscus	100972224		PANPA19363
Papio anubis	101008648		PAPAN21850
Saimiri boliviensis boliviensis	101048803		SAIBB30908
Ovis aries	101102807		SHEEP16343
Gorilla gorilla gorilla	101134573		GORGO15758
Octodon degus	101565994	10160_0:0043a9	OCTDE23323
Jaculus jaculus	101618080	51337_0:001da1	JACJA24275
Mustela putorius furo	101687398		MUSPF05242
Heterocephalus glaber	101715897	10181_0:003c29
Mesocricetus auratus	101839938	10036_0:004d15

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements