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DNA polymerase delta 1, catalytic subunit

Summary

Gene Symbol

POLD1

Organism

Homo sapiens (human)

External Links

NCBI Gene

5424

PubChem

5424

Alliance of Genome Resources

HGNC:9175

JoGo

POLD1

TogoVar

POLD1

Annotation

Keyword

3D-structure
4Fe-4S
DNA excision
DNA repair
DNA replication
DNA-binding
DNA-directed DNA polymerase
Disease variant
Exonuclease
Isopeptide bond
Methylation
Nucleus
Proteomics identification
Reference proteome
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 5** entries
UniProt	Protein Name
A0A087WYJ2
M0R2B7
Q308M6
Q59FA0
P28340	3'-5' exodeoxyribonuclease DNA polymerase subunit delta p125

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
DNA synthesis involved in DNA repair	IDA	24191025 3335506
DNA synthesis involved in DNA repair	IMP	1730053
DNA replication	IMP	16762037
DNA-templated DNA replication	IDA	20334433
DNA-templated DNA replication	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA replication

DNA-templated DNA replication

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

DNA-templated DNA replication maintenance of fidelity [inference]

DNA replication proofreading

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process

DNA synthesis involved in DNA repair

translesion synthesis [inference]

error-free translesion synthesis

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

fatty acid homeostasis

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV

cellular response to UV

cellular response to light stimulus [inference]

cellular response to UV

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

postreplication repair [inference]

translesion synthesis [inference]

error-free translesion synthesis

DNA replication proofreading

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus [inference]

cellular response to UV

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
nucleotide-excision repair complex	IDA	20713449
chromosome, telomeric region	IDA	24270157
nucleus	IDA	16762037
nucleoplasm	TAS
nucleoplasm	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

intracellular protein-containing complex [inference]

DNA polymerase complex [inference]

delta DNA polymerase complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

DNA polymerase complex [inference]

delta DNA polymerase complex

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
nucleotide binding	IEA
DNA binding	IDA	16762037
chromatin binding	IDA	16762037 24939902
damaged DNA binding	IDA	24939902
DNA-directed DNA polymerase activity	IMP	16762037