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ATPase, H+ transporting, lysosomal accessory protein 1

Summary

Gene Symbol

Atp6ap1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

54411

PubChem

54411

Alliance of Genome Resources

MGI:109629

Annotation

Keyword

Cytoplasmic vesicle
Direct protein sequencing
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Hydrogen ion transport
Reference proteome
Signal
Synapse
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9R1Q9	Protein C7-1 V-ATPase Ac45 subunit V-ATPase S1 accessory protein Vacuolar proton pump subunit S1
Q3TWN7
Q3UWN7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
intracellular iron ion homeostasis	ISS
intracellular iron ion homeostasis	ISO
regulation of cellular pH	IBA
osteoclast development	IMP	22467241
cellular response to increased oxygen levels	ISS

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

osteoclast development

bone cell development [inference]

osteoclast development

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

synaptic vesicle lumen acidification

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport [inference]

synaptic vesicle lumen acidification

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

proton-transporting two-sector ATPase complex assembly [inference]

proton-transporting V-type ATPase complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

proton-transporting two-sector ATPase complex assembly [inference]

proton-transporting V-type ATPase complex assembly

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

osteoclast development

bone cell development [inference]

osteoclast development

cellular developmental process [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

osteoclast development

bone cell development [inference]

osteoclast development

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

neuron cellular homeostasis [inference]

synaptic vesicle lumen acidification

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH

intracellular monoatomic cation homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

inorganic ion homeostasis [inference]

intracellular iron ion homeostasis

response to stimulus [inference]

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to increased oxygen levels [inference]

cellular response to increased oxygen levels

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to increased oxygen levels

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

synaptic vesicle lumen acidification

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

synaptic vesicle lumen acidification

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport [inference]

synaptic vesicle lumen acidification

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport [inference]

synaptic vesicle lumen acidification

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

synaptic vesicle lumen acidification

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

endosomal transport [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling [inference]

endosome to plasma membrane protein transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to membrane [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

establishment of protein localization to membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

protein localization to cell periphery [inference]

protein localization to plasma membrane [inference]

establishment of protein localization to plasma membrane [inference]

endosome to plasma membrane protein transport

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
endosome membrane	IMP	22087256
membrane	ISO
clathrin-coated vesicle membrane	IEA
synaptic vesicle membrane	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

catalytic complex [inference]

ATPase complex [inference]

proton-transporting two-sector ATPase complex [inference]

proton-transporting V-type ATPase complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane

bounding membrane of organelle [inference]

endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

coated vesicle membrane [inference]

clathrin-coated vesicle membrane

endoplasmic reticulum-Golgi intermediate compartment membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ATPase activator activity	IMP	22087256
ATPase activator activity	IBA
small GTPase binding	IPI	22467241
transporter activator activity	IMP	22087256

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

molecular function regulator activity [inference]

ATPase regulator activity [inference]

ATPase activator activity

molecular function activator activity [inference]

transporter regulator activity [inference]

transporter activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

V-type proton ATPase subunit

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
(1->6)-beta-D-glucan biosynthetic process
fungal-type cell wall biogenesis

Displaying 1 entry
InterPro
V-type proton ATPase subunit S1/VOA1, transmembrane domain

Ortholog

Displaying entries **1 - 10** of 67 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	537	Xenbase:XB-GENE-997187	HUMAN102878
Xenopus tropicalis	35944	Xenbase:XB-GENE-997187
Xenopus tropicalis	54411	Xenbase:XB-GENE-997187
Xenopus tropicalis	65125	Xenbase:XB-GENE-997187
Rattus norvegicus	83615	Xenbase:XB-GENE-997187	RATNO44190
Xenopus tropicalis	116477	Xenbase:XB-GENE-997187
Xenopus tropicalis	177103	Xenbase:XB-GENE-997187
Xenopus tropicalis	232341	Xenbase:XB-GENE-997187
Bos taurus	327687		BOVIN36546
Pan troglodytes	740281		PANTR47137

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements