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anillin, actin binding protein

Summary

Gene Symbol

ANLN

Organism

Homo sapiens (human)

External Links

NCBI Gene

54443

PubChem

54443

Alliance of Genome Resources

HGNC:14082

Annotation

Keyword

3D-structure
Acetylation
Actin-binding
Alternative splicing
Cell projection
Coiled coil
Cytoskeleton
Disease variant
Isopeptide bond
Mitosis
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8K5D9
Q9NQW6

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
mitotic cytokinesis	IDA	10931866
mitotic cytokinesis	IBA
actomyosin contractile ring assembly	IBA
septin ring assembly	TAS	10931866
hematopoietic progenitor cell differentiation	IEA

GO Hierarchy

biological process

cellular process [inference]

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

cytokinetic process [inference]

assembly of actomyosin apparatus involved in cytokinesis [inference]

actomyosin contractile ring assembly

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

mitotic cell cycle process [inference]

mitotic cytokinesis

actin filament-based process [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

actomyosin structure organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

podocyte cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

actomyosin structure organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

cortical cytoskeleton organization [inference]

cortical actin cytoskeleton organization [inference]

actomyosin contractile ring organization [inference]

actomyosin contractile ring assembly

septin cytoskeleton organization [inference]

septin ring organization

septin ring assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

septin ring assembly

cellular component assembly [inference]

assembly of actomyosin apparatus involved in cytokinesis [inference]

actomyosin contractile ring assembly

protein-containing complex assembly [inference]

septin ring assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

septin ring assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

septin ring assembly

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

hematopoietic progenitor cell differentiation

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of bleb assembly [inference]

positive regulation of bleb assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of bleb assembly [inference]

positive regulation of bleb assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of bleb assembly [inference]

positive regulation of bleb assembly

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of plasma membrane bounded cell projection assembly [inference]

positive regulation of bleb assembly

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis

regulation of cell cycle process [inference]

regulation of cell cycle phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of exit from mitosis

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleoplasm	IDA
actomyosin contractile ring	IDA	10931866
actomyosin contractile ring	IBA
cytosol	TAS
cell cortex	IDA	23870127

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

cytoplasm [inference]

cell cortex

cell projection [inference]

plasma membrane bounded cell projection [inference]

bleb

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

contractile ring [inference]

actomyosin contractile ring

Displaying **all 3** entries
GO Term	Evidence Code	PMID
actin binding	IDA	10931866
protein binding	IPI	25416956
cadherin binding	HDA	25468996

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding

cell adhesion molecule binding [inference]

cadherin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

anillin

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
mitotic cytokinesis
septin ring organization

Displaying **all 4** entries
InterPro
Anillin homology domain
Anillin, PH domain
PH-like domain superfamily
Pleckstrin homology domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111133	focal segmental glomerulosclerosis 8	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	54443	ZFIN:ZDB-GENE-030131-4486
Mus musculus	68743	ZFIN:ZDB-GENE-030131-4486	MOUSE63473
Rattus norvegicus	363031		RATNO40838
Pan troglodytes	463351		PANTR40036
Canis lupus familiaris	482401		CANLF03820
Bos taurus	518274		BOVIN28044
Danio rerio	562517		DANRE15033
Macaca mulatta	706404		MACMU31168
Equus caballus	100070572		HORSE33439
Ornithorhynchus anatinus	100086188		ORNAN14113