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Standards Ontologies Notations
N-acylsphingosine amidohydrolase 2

Summary
Gene Symbol
  • Asah2
Organism
Mus musculus (house mouse)
NCBI Gene
54447
PubChem
54447
Alliance of Genome Resources
Annotation
Keyword
  • Apoptosis
  • Calcium
  • Cell membrane
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Golgi apparatus
  • Hydrolase
  • Metal-binding
  • Mitochondrion
  • Phosphoprotein
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Sphingolipid metabolism
  • Transmembrane helix
  • Ubl conjugation
  • Zinc
Proteins
Displaying all 2 entries
UniProt Protein Name
B9EHG7
Q9JHE3
  • Acylsphingosine deacylase 2
  • N-acylsphingosine amidohydrolase 2
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Rodentia
Group Name
neutral ceramidase
Functional Category
  • I: Lipid transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
Displaying all 9 entries
Gene Ontology
N-acylsphingosine amidohydrolase activity
ceramidase activity
ceramide catabolic process
ceramide metabolic process
hydrolase activity
lipid metabolic process
long-chain fatty acid biosynthetic process
sphingolipid metabolic process
sphingosine biosynthetic process
Displaying all 4 entries
InterPro
Neutral ceramidase, C-terminal domain superfamily
Neutral/alkaline non-lysosomal ceramidase, C-terminal
Neutral/alkaline non-lysosomal ceramidase, N-terminal
Neutral/alkaline nonlysosomal ceramidase
Rhea

RHEA:20856

H2O + an N-acylsphing-4-enine
a fatty acid + sphing-4-enine
Enzyme
PMID
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0050700 cardiomyopathy
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP006314
Gene Name
N-acylsphingosine amidohydrolase 2
Ortholog
Displaying entries 21 - 30 of 86 in total
Species Gene ID OrthoDB Alliance of Genome Resources Orthologous MAtrix
100957185 OTOGA17198
101097670 FELCA26378
101121732 SHEEP11406
101146782 GORGO01537
101165218 ORYLA19924
101571658 10160_0:0003e7 OCTDE01726
101599043 51337_0:000a7c JACJA04378
101688600 MUSPF08490
101709668 10181_0:002d59
101825267 10036_0:000271
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024