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reticulophagy regulator 1

Summary

Gene Symbol

RETREG1

Organism

Homo sapiens (human)

External Links

NCBI Gene

54463

PubChem

54463

Alliance of Genome Resources

HGNC:25964

JoGo

RETREG1

TogoVar

RETREG1

Annotation

Keyword

3D-structure
Alternative splicing
Autophagy
Endoplasmic reticulum
Golgi apparatus
Neurodegeneration
Neuropathy
Phosphoprotein
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A804HHX5
Q9H6L5	Reticulophagy receptor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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2

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GO Term	Evidence Code	PMID
mitophagy	IEA
endoplasmic reticulum organization	IEA
sensory perception of pain	IMP	19838196
collagen catabolic process	IEA
negative regulation of neuron apoptotic process	IMP	26040720

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

collagen catabolic process

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

collagen metabolic process [inference]

collagen catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation [inference]

white fat cell differentiation

process utilizing autophagic mechanism [inference]

autophagy [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

autophagy of mitochondrion [inference]

mitophagy

endoplasmic reticulum organization

organelle disassembly [inference]

autophagy of mitochondrion [inference]

mitophagy

reticulophagy

cellular component disassembly [inference]

organelle disassembly [inference]

autophagy of mitochondrion [inference]

mitophagy

reticulophagy

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of pain

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation [inference]

white fat cell differentiation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular process [inference]

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleolus	IDA
endoplasmic reticulum	IDA	35239449
endoplasmic reticulum membrane	IDA	26040720
endoplasmic reticulum membrane	IBA
cis-Golgi network	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

nuclear body

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	26040720 32296183 32814053 34524948
endoplasmic reticulum-autophagosome adaptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

protein-membrane adaptor activity [inference]

endoplasmic reticulum-organelle membrane tether activity [inference]

endoplasmic reticulum-autophagosome adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

reticulophagy regulator 1

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
negative regulation of neuron apoptotic process

Displaying 1 entry
InterPro
Reticulophagy receptor 1/3

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070150	hereditary sensory and autonomic neuropathy type 2B	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements