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heparanase 2

Summary

Gene Symbol

Hpse2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

545291

PubChem

545291

Alliance of Genome Resources

MGI:2685814

Annotation

Keyword

Extracellular matrix
Glycoprotein
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
B2RY83

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	25510506
cell population proliferation	IMP	25510506
extracellular matrix organization	IBA IMP	25510506

GO Hierarchy

biological process

cellular process [inference]

cell population proliferation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular matrix	IBA IEA ISO
membrane	IEA
extracellular region	IEA
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

Displaying **all 2** entries
GO Term	Evidence Code	PMID
heparan sulfate proteoglycan binding	IEA ISO
hydrolase activity, acting on glycosyl bonds	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds

binding [inference]

protein binding [inference]

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

carbohydrate derivative binding [inference]

proteoglycan binding [inference]

heparan sulfate proteoglycan binding

sulfur compound binding [inference]

heparan sulfate proteoglycan binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

inactive heparanase-2

Functional Category

J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms
V: Defense mechanisms

Displaying **all 2** entries
Gene Ontology
extracellular matrix organization
hydrolase activity, acting on glycosyl bonds

Displaying **all 2** entries
InterPro
Glycoside hydrolase superfamily
Glycoside hydrolase, family 79

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050816	urofacial syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of **100** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Esox lucius	105021381		ESOLU17193
Macaca nemestrina	105478425		MACNE28060
Mandrillus leucophaeus	105554353		MANLE13757
Cercocebus atys	105581816		CERAT19857
Aotus nancymaae	105708268		AOTNA16751
Propithecus coquereli	105824287		PROCO10491
Dipodomys ordii	105986655	10020_0:001ce5	DIPOR07197
Salmo salar	106612917		SALSA66621
Cyprinodon variegatus	107088632		CYPVA00260
Marmota marmota marmota	107149782	9994_0:001c70

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements