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UDP glucuronosyltransferase family 1 member A10

Summary

Gene Symbol

UGT1A10

Aliases

UGT1J

Organism

Homo sapiens (human)

External Links

NCBI Gene

54575

HGNC

12531

KEGG Gene ID

hsa:54575

PubChem

54575

Alliance of Genome Resources

HGNC:12531

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Lipid metabolism
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q5DT02
Q9HAW8	UDP-glucuronosyltransferase 1-10 UDP-glucuronosyltransferase 1-J

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
liver development	IBA
lipid metabolic process	IEA
xenobiotic metabolic process	TAS
xenobiotic metabolic process	IDA	20056724
xenobiotic metabolic process	IMR	20610558

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

secondary metabolic process [inference]

toxin metabolic process [inference]

toxin catabolic process

pigment metabolic process [inference]

flavone metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

xenobiotic metabolic process

xenobiotic catabolic process

toxin metabolic process [inference]

toxin catabolic process

cellular catabolic process [inference]

primary metabolic process [inference]

lipid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

lipid metabolic process

flavonoid metabolic process [inference]

flavone metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

xenobiotic metabolic process

xenobiotic catabolic process

toxin metabolic process [inference]

toxin catabolic process

cellular catabolic process [inference]

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

liver development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of carbohydrate metabolic process [inference]

negative regulation of cellular glucuronidation

negative regulation of small molecule metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

negative regulation of cellular metabolic process [inference]

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

negative regulation of small molecule metabolic process [inference]

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

negative regulation of carbohydrate metabolic process [inference]

negative regulation of cellular glucuronidation

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of lipid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of carbohydrate metabolic process [inference]

negative regulation of cellular glucuronidation

negative regulation of small molecule metabolic process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

detoxification [inference]

toxin catabolic process

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum	NAS	20610558
endoplasmic reticulum	IDA	17179145 18556656
endoplasmic reticulum	IBA
endoplasmic reticulum membrane	NAS	20610558
endoplasmic reticulum membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
retinoic acid binding	IDA	20308471
enzyme inhibitor activity	ISS	20610558
protein kinase C binding	IPI	18556656
protein binding	IPI	18556656
glucuronosyltransferase activity	ISS	20610558

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding

enzyme binding

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

glucuronosyltransferase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
UDP-glycosyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
UDP-glucuronosyl/UDP-glucosyltransferase
UDP-glycosyltransferase family, conserved site

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Rhea

RHEA:21032

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

Ortholog

Displaying entries **31 - 40** of **148** in total

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Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	53501	Xenbase:XB-GENE-998849
Xenopus tropicalis	53502	Xenbase:XB-GENE-998849
Xenopus tropicalis	53503	Xenbase:XB-GENE-998849
Xenopus tropicalis	53504	Xenbase:XB-GENE-998849
Xenopus tropicalis	53506	Xenbase:XB-GENE-998849
Xenopus tropicalis	53507	Xenbase:XB-GENE-998849
Xenopus tropicalis	53511	Xenbase:XB-GENE-998849
Xenopus tropicalis	53512	Xenbase:XB-GENE-998849
Xenopus tropicalis	53513	Xenbase:XB-GENE-998849
Xenopus tropicalis	53583	Xenbase:XB-GENE-998849