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UDP glucuronosyltransferase family 1 member A9

Summary

Gene Symbol

UGT1A9

Aliases

HLUGP4
LUGP4
UGT1AI

Organism

Homo sapiens (human)

External Links

NCBI Gene

54600

HGNC

12541

KEGG Gene ID

hsa:54600

PubChem

54600

Alliance of Genome Resources

HGNC:12541

Annotation

Keyword

Alternative splicing
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Lipid metabolism
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q5DSZ5
O60656	UDP-glucuronosyltransferase 1-9 UDP-glucuronosyltransferase 1-I lugP4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
flavonoid glucuronidation	IDA	20056724
negative regulation of cellular glucuronidation	IDA	18004212 20610558
xenobiotic metabolic process	IDA TAS	1910331 20610558
flavone metabolic process	IDA	18052087
retinoic acid metabolic process	IC	20308471

GO Hierarchy

biological process

metabolic process [inference]

pigment metabolic process [inference]

flavone metabolic process

hormone metabolic process [inference]

retinoic acid metabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

retinoic acid metabolic process

xenobiotic metabolic process

xenobiotic glucuronidation

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

retinoic acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

retinoic acid metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process

flavonoid metabolic process [inference]

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

retinoic acid metabolic process

xenobiotic metabolic process

xenobiotic glucuronidation

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinoic acid metabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

liver development

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of carbohydrate metabolic process [inference]

negative regulation of cellular glucuronidation

negative regulation of small molecule metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

negative regulation of cellular metabolic process [inference]

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

negative regulation of small molecule metabolic process [inference]

regulation of primary metabolic process [inference]

regulation of carbohydrate metabolic process [inference]

negative regulation of carbohydrate metabolic process [inference]

negative regulation of cellular glucuronidation

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

regulation of lipid metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of lipid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of lipid metabolic process [inference]

negative regulation of fatty acid metabolic process

negative regulation of carbohydrate metabolic process [inference]

negative regulation of cellular glucuronidation

negative regulation of small molecule metabolic process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of fatty acid metabolic process [inference]

negative regulation of fatty acid metabolic process

regulation of cellular glucuronidation [inference]

negative regulation of cellular glucuronidation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinoic acid metabolic process

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of glucuronosyltransferase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of glucuronosyltransferase activity

regulation of transferase activity [inference]

negative regulation of transferase activity [inference]

negative regulation of glucuronosyltransferase activity

regulation of glucuronosyltransferase activity [inference]

negative regulation of glucuronosyltransferase activity

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IKR IMR NAS TAS	20610558
endoplasmic reticulum	IBA IDA NAS	17179145 20610558

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
glucuronosyltransferase activity	IDA IGI ISS TAS	18052087 20056724 20308471 20610558 22579593
enzyme inhibitor activity	IDA IGI	20610558
protein homodimerization activity	IDA	17179145

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding

enzyme binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

retinoic acid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Glucuronosyltransferase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
UDP-glycosyltransferase activity
transferase activity

Displaying 1 entry
InterPro
UDP-glucuronosyl/UDP-glucosyltransferase

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Rhea

RHEA:21032

glucuronate acceptor + UDP-α-D-glucuronate

acceptor β-D-glucuronoside + H⁺ + UDP

Enzyme

2.4.1.17

PMID

Ortholog

Displaying entries **11 - 20** of 69 in total

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Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	42774	FB:FBgn0039085
Drosophila melanogaster	42775	FB:FBgn0039086
Drosophila melanogaster	53501	FB:FBgn0040250
Drosophila melanogaster	53502	FB:FBgn0040251
Drosophila melanogaster	53503	FB:FBgn0040252
Drosophila melanogaster	53506	FB:FBgn0040255
Drosophila melanogaster	53507	FB:FBgn0040256
Drosophila melanogaster	53508	FB:FBgn0040257
Drosophila melanogaster	53511	FB:FBgn0040260
Drosophila melanogaster	53512	FB:FBgn0040261