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frizzled class receptor 7

Summary

Gene Symbol

fzd7

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

549495

PubChem

549495

Alliance of Genome Resources

Xenbase:XB-GENE-483731

Annotation

Keyword

Cell membrane
Developmental protein
Disulfide bond
Endosome
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q5BL72

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
gastrulation with mouth forming second	IMP	17112317
mesoderm formation	ISS
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	IEA
protein localization	ISS

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

multicellular organismal process [inference]

pattern specification process [inference]

axis specification [inference]

dorsal/ventral axis specification

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

gastrulation [inference]

gastrulation with mouth forming second

convergent extension involved in gastrulation

tissue morphogenesis

morphogenesis of an epithelium [inference]

convergent extension [inference]

convergent extension involved in gastrulation

anatomical structure formation involved in morphogenesis [inference]

formation of primary germ layer [inference]

mesoderm formation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway

G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic signaling pathway

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
endosome	IEA
plasma membrane	ISS
plasma membrane	IEA
endosome membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IEA
G protein-coupled receptor activity	IEA
Wnt-protein binding	ISS
syndecan binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

Wnt-protein binding

proteoglycan binding [inference]

syndecan binding

carbohydrate derivative binding [inference]

proteoglycan binding [inference]

syndecan binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Frizzled

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
Wnt receptor activity
Wnt-protein binding
canonical Wnt signaling pathway
cell surface receptor signaling pathway
non-canonical Wnt signaling pathway

Displaying **all 5** entries
InterPro
Frizzled cysteine-rich domain superfamily
Frizzled domain
Frizzled/Smoothened, 7TM
Frizzled/secreted frizzled-related protein
GPCR, family 2-like, 7TM

Ortholog

Displaying entries **1 - 10** of 27 in total

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Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	2535	FB:FBgn0001085
Caenorhabditis elegans	7855	WB:WBGene00000478
Caenorhabditis elegans	7976	WB:WBGene00003397
Drosophila melanogaster	8321	FB:FBgn0001085
Caenorhabditis elegans	8323	WB:WBGene00003397
Xenopus laevis	8324	Xenbase:XB-GENE-483735
Caenorhabditis elegans	8325	WB:WBGene00000478
Caenorhabditis elegans	8326	WB:WBGene00000478
Caenorhabditis elegans	11211	WB:WBGene00000478
Drosophila melanogaster	14362	FB:FBgn0001085