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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

protein phosphatase 1 catalytic subunit gamma

Summary

Gene Symbol

PPP1CC

Organism

Homo sapiens (human)

External Links

NCBI Gene

5501

PubChem

5501

Alliance of Genome Resources

HGNC:9283

JoGo

PPP1CC

TogoVar

PPP1CC

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
mitotic sister chromatid segregation	TAS
MAPK cascade	TAS
blastocyst development	IEA
glycogen metabolic process	IEA
chromatin remodeling	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

MAPK cascade

cell cycle process [inference]

chromosome segregation [inference]

nuclear chromosome segregation [inference]

sister chromatid segregation [inference]

mitotic sister chromatid segregation

mitotic cell cycle process [inference]

mitotic sister chromatid segregation

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

sister chromatid segregation [inference]

mitotic sister chromatid segregation

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

anatomical structure development [inference]

blastocyst development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

rhythmic process [inference]

circadian rhythm [inference]

circadian regulation of gene expression

response to stimulus [inference]

response to external stimulus [inference]

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

photoperiodism [inference]

entrainment of circadian clock by photoperiod

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

circadian regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

circadian regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

circadian regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport

regulation of circadian rhythm

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

MAPK cascade

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

circadian regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation

regulation of glial cell proliferation [inference]

positive regulation of glial cell proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of glial cell proliferation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

Displaying entries **6 - 10** of 21 in total

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GO Term	Evidence Code	PMID
nucleolus	IDA	11739654
cytoplasm	IDA	11739654
cytoplasm	IBA
mitochondrion	IDA	17936702
mitochondrial outer membrane	IEA

GO Hierarchy

cellular component

protein-containing complex

catalytic complex [inference]

phosphatase complex [inference]

protein serine/threonine phosphatase complex [inference]

protein phosphatase type 1 complex [inference]

PTW/PP1 phosphatase complex

cellular anatomical entity [inference]

membrane [inference]

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

plasma membrane region [inference]

cleavage furrow

nuclear body [inference]

nuclear speck

cell junction [inference]

synapse [inference]

glutamatergic synapse

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

midbody

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosomal region [inference]

chromosome, telomeric region

presynapse

postsynapse [inference]

dendritic spine

supramolecular complex [inference]

kinetochore

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
RNA binding	HDA	22681889
phosphoprotein phosphatase activity	TAS
protein serine/threonine phosphatase activity	TAS
protein serine/threonine phosphatase activity	IDA	25012651
protein serine/threonine phosphatase activity	IMP	10880350 17936702

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

phosphoprotein phosphatase activity

protein serine/threonine phosphatase activity

calcium-dependent protein serine/threonine phosphatase activity [inference]

calmodulin-dependent protein phosphatase activity

RNA polymerase II CTD heptapeptide repeat phosphatase activity [inference]

MAP kinase phosphatase activity [inference]

MAP kinase serine/threonine phosphatase activity

histone phosphatase activity [inference]

histone H2AXS140 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein serine/threonine phosphatase activity

calcium-dependent protein serine/threonine phosphatase activity [inference]

calmodulin-dependent protein phosphatase activity

RNA polymerase II CTD heptapeptide repeat phosphatase activity [inference]

MAP kinase phosphatase activity [inference]

MAP kinase serine/threonine phosphatase activity

histone phosphatase activity [inference]

histone H2AXS140 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXS140 phosphatase activity

RNA polymerase II CTD heptapeptide repeat modifying activity [inference]

RNA polymerase II CTD heptapeptide repeat phosphatase activity [inference]

binding [inference]

protein binding

lamin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

phosphatase binding [inference]

protein phosphatase binding [inference]

protein phosphatase 1 binding

protein domain specific binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 2** entries
Gene Ontology
hydrolase activity
phosphoprotein phosphatase activity

Displaying **all 4** entries
InterPro
Calcineurin-like phosphoesterase domain, ApaH type
Metallo-dependent phosphatase-like
Serine/Threonine protein phosphatase PP2A-like
Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026