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molybdenum cofactor sulfurase

Summary

Gene Symbol

MOCOS

Organism

Homo sapiens (human)

External Links

NCBI Gene

55034

PubChem

55034

Alliance of Genome Resources

HGNC:18234

Annotation

Keyword

Disease variant
Molybdenum cofactor biosynthesis
Phosphoprotein
Pyridoxal phosphate
Reference proteome
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96EN8	Molybdenum cofactor sulfurtransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
Mo-molybdopterin cofactor biosynthetic process	IEA
molybdopterin cofactor biosynthetic process	TAS
molybdopterin cofactor metabolic process	IMP	11302742
molybdopterin cofactor metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organonitrogen compound biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organic cyclic compound biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organonitrogen compound biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organophosphate metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organophosphate biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

prosthetic group metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organophosphate biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organic cyclic compound metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organic cyclic compound biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organonitrogen compound metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organonitrogen compound biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organic cyclic compound biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organonitrogen compound biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organophosphate metabolic process [inference]

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

organophosphate biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

cellular biosynthetic process [inference]

heterocycle biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor metabolic process

Mo-molybdopterin cofactor metabolic process [inference]

Mo-molybdopterin cofactor biosynthetic process

molybdopterin cofactor biosynthetic process

Mo-molybdopterin cofactor biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	21516116 25416956 28514442 32296183 33961781
Mo-molybdopterin cofactor sulfurase activity	TAS
Mo-molybdopterin cofactor sulfurase activity	IMP	11302742
Mo-molybdopterin cofactor sulfurase activity	IBA
lyase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfurtransferase activity [inference]

Mo-molybdopterin cofactor sulfurase activity

lyase activity

binding [inference]

protein binding

small molecule binding [inference]

vitamin binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

heterocyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

pyridoxal phosphate binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

molybdenum ion binding

organic cyclic compound binding [inference]

vitamin B6 binding [inference]

pyridoxal phosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Molybdenum cofactor sulfurase

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
catalytic activity

Displaying **all 4** entries
InterPro
Aminotransferase class V domain
Pyridoxal phosphate-dependent transferase, major domain
Pyridoxal phosphate-dependent transferase, small domain
Pyridoxal phosphate-dependent transferase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070453	xanthinuria type II	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 93 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	55034	ZFIN:ZDB-GENE-050327-94
Mus musculus	68591		MOUSE23364
Bos taurus	281226		BOVIN19451
Rattus norvegicus	361300		RATNO13885
Pan troglodytes	455379		PANTR16166
Canis lupus familiaris	490482		CANLF17527
Macaca mulatta	715633		MACMU17605
Monodelphis domestica	100013356		MONDO19845
Ornithorhynchus anatinus	100075210		ORNAN31001
Taeniopygia guttata	100221503		TAEGU17779