GlyCosmos Portal

Submissions

pentatricopeptide repeat domain 3

Summary

Gene Symbol

PTCD3

Organism

Homo sapiens (human)

External Links

NCBI Gene

55037

PubChem

55037

Alliance of Genome Resources

HGNC:24717

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Mitochondrion
Primary mitochondrial disease
Proteomics identification
Reference proteome
Repeat
Ribosomal protein
Transit peptide
Translation regulation
rRNA-binding

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96EY7	28S ribosomal protein S39, mitochondrial Pentatricopeptide repeat domain-containing protein 3, mitochondrial Transformation-related gene 15 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
regulation of translation	IEA
mitochondrial translation	NAS	27023846
mitochondrial translation	IMP	19427859
mitochondrial translation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

primary metabolic process [inference]

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

protein metabolic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

translation [inference]

mitochondrial translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

translation [inference]

mitochondrial translation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

regulation of translation

regulation of protein metabolic process [inference]

regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of protein metabolic process [inference]

regulation of translation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
nucleoplasm	IDA
mitochondrion	IDA	19427859
mitochondrion	IBA
mitochondrion	HTP	34800366
mitochondrial inner membrane	NAS	27023846

GO Hierarchy

cellular component

protein-containing complex [inference]

mitochondrial protein-containing complex [inference]

mitochondrial small ribosomal subunit

ribonucleoprotein complex [inference]

ribosomal subunit [inference]

small ribosomal subunit [inference]

organellar small ribosomal subunit [inference]

mitochondrial small ribosomal subunit

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
RNA binding	HDA	22658674 22681889
protein binding	IPI	19427859 21516116 24965446 29892012 31515488 33961781
rRNA binding	IDA	19427859
rRNA binding	IBA
ribosomal small subunit binding	IDA	19427859

GO Hierarchy

molecular function

binding [inference]

protein binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

ribosome binding [inference]

ribosomal small subunit binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

rRNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Pentatricopeptide repeat-containing protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
mitochondrial translation
ribosomal small subunit binding

Displaying **all 3** entries
InterPro
Pentatricopeptide repeat domain-containing protein 3
Pentatricopeptide repeat
Tetratricopeptide-like helical domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0112137	combined oxidative phosphorylation deficiency 51	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 76 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	55037	Xenbase:XB-GENE-961480
Mus musculus	69956		MOUSE48077
Pan troglodytes	459374		PANTR28090
Canis lupus familiaris	475765		CANLF05160
Rattus norvegicus	500199		RATNO31996
Bos taurus	509502		BOVIN02555
Danio rerio	553325		DANRE07319
Macaca mulatta	697081		MACMU07581
Monodelphis domestica	100029855		MONDO05116
Equus caballus	100067047		HORSE00089