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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

elongator acetyltransferase complex subunit 2

Summary

Gene Symbol

ELP2

Organism

Homo sapiens (human)

External Links

NCBI Gene

55250

PubChem

55250

Alliance of Genome Resources

HGNC:18248

JoGo

ELP2

TogoVar

ELP2

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Disease variant
Intellectual disability
Nucleus
Proteomics identification
Reference proteome
Repeat
WD repeat
tRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6IA86	SHINC-2 STAT3-interacting protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
tRNA wobble uridine modification	NAS	27847465
regulation of transcription by RNA polymerase II	TAS	11714725
transcription elongation by RNA polymerase II	TAS	11714725
regulation of translation	NAS	22854966
regulation of receptor signaling pathway via JAK-STAT	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

macromolecule modification [inference]

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA modification [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

ncRNA metabolic process [inference]

tRNA metabolic process [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

ncRNA processing [inference]

tRNA processing [inference]

tRNA modification [inference]

tRNA wobble base modification [inference]

tRNA wobble uridine modification

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase II

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of amide metabolic process [inference]

regulation of translation

regulation of protein metabolic process [inference]

regulation of translation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of translation

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of translation

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
nucleoplasm	IDA
cytoplasm	NAS	11714725
cytosol	IDA
transcription elongation factor complex	IDA	11714725
elongator holoenzyme complex	IDA	22854966

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

transcription elongation factor complex

intracellular protein-containing complex [inference]

elongator holoenzyme complex

catalytic complex [inference]

elongator holoenzyme complex

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
RNA polymerase II complex binding	IDA	11714725
protein kinase binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

basal transcription machinery binding [inference]

basal RNA polymerase II transcription machinery binding [inference]

RNA polymerase II complex binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

RNA polymerase binding [inference]

RNA polymerase core enzyme binding [inference]

RNA polymerase II complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

elongator complex

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
tRNA processing
tRNA wobble uridine modification

Displaying **all 4** entries
InterPro
Elongator complex protein 2
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0081220	autosomal recessive intellectual developmental disorder 58	Alliance of Genome Resources

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026