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Guidelines

MIRAGE

interacts with SUPT6H, CTD assembly factor 1

Summary

Gene Symbol

IWS1

Organism

Homo sapiens (human)

External Links

NCBI Gene

55677

PubChem

55677

Alliance of Genome Resources

HGNC:25467

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Nucleus
Phosphoprotein
Reference proteome
Repeat
Transcription regulation
mRNA splicing
mRNA transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96ST2	IWS1-like protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
chromatin remodeling	IMP	19141475
mRNA processing	IEA
RNA splicing	IEA
regulation of mRNA export from nucleus	IMP	17234882
poly(A)+ mRNA export from nucleus	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA metabolic process [inference]

mRNA processing

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

transcription elongation-coupled chromatin remodeling

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

organic substance transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

cellular localization [inference]

intracellular transport [inference]

nuclear transport [inference]

nucleocytoplasmic transport [inference]

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus [inference]

poly(A)+ mRNA export from nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of macromolecule metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of localization [inference]

regulation of transport [inference]

regulation of nucleobase-containing compound transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of ribonucleoprotein complex localization [inference]

regulation of mRNA export from nucleus

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of nucleocytoplasmic transport [inference]

regulation of RNA export from nucleus [inference]

regulation of mRNA export from nucleus

regulation of ribonucleoprotein complex localization [inference]

regulation of mRNA export from nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
nucleus	IDA	17234882
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	17234882 19141475 25689719 26245978 29997176

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

IWS1 protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
poly(A)+ mRNA export from nucleus

Displaying **all 2** entries
InterPro
TFIIS/LEDGF domain superfamily
Transcription factor IIS, N-terminal

Ortholog

Displaying entries **1 - 10** of 77 in total

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	55677	Xenbase:XB-GENE-6458249
Mus musculus	73473		MOUSE23476
Rattus norvegicus	291705		RATNO14027
Canis lupus familiaris	476103		CANLF06321
Bos taurus	538614		BOVIN23855
Macaca mulatta	699205		MACMU05767
Pan troglodytes	738706		PANTR28610
Xenopus tropicalis	856251	Xenbase:XB-GENE-6458249
Monodelphis domestica	100026604		MONDO24350
Ornithorhynchus anatinus	100079588		ORNAN11911

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025