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MIRAGE
CDK5 regulatory subunit associated protein 2
Summary
- Gene Symbol
-
- CDK5RAP2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calmodulin-binding
- Coiled coil
- Cytoskeleton
- Golgi apparatus
- Intellectual disability
- Microtubule
- Phosphoprotein
- Primary microcephaly
- Proteomics identification
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8I5KXG0 |
|
| B9EG74 |
|
| A0A8I5QKL1 |
|
| B3KVI2 |
|
| A0A0A0MRG9 |
|
| Q96SN8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| establishment of mitotic spindle orientation | ||
| establishment of mitotic spindle orientation | ||
| microtubule cytoskeleton organization | ||
| microtubule bundle formation | ||
| microtubule bundle formation |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of microtubule-based process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell cycle [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| pericentriolar material | ||
| pericentriolar material | ||
| spindle pole | ||
| gamma-tubulin ring complex | ||
| cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| transcription cis-regulatory region binding | ||
| protein binding | ||
| calmodulin binding | ||
| microtubule binding | ||
| microtubule binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cdk5 regulatory subunit-associated protein 2
- Functional Category
-
- L: Replication, recombination and repair
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| microtubule cytoskeleton organization |
| InterPro |
|---|
| Centrosomin, N-terminal motif 1 |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050569 | Seckel syndrome | |
| DOID:0070286 | primary autosomal recessive microcephaly 3 | |
| DOID:10907 | microcephaly |
