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MIRAGE
tyrosyl-DNA phosphodiesterase 1

Summary
Gene Symbol
  • TDP1
Organism
Homo sapiens (human)
NCBI Gene
55775
PubChem
55775
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cytoplasm
  • DNA repair
  • Disease variant
  • Exonuclease
  • Neurodegeneration
  • Nuclease
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repeat
Proteins
Displaying all 3 entries
UniProt Protein Name
G3V2F4
B3KN41
Q9NUW8
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 5 entries
GO Term Evidence Code PMID
single strand break repair
single strand break repair
DNA repair
DNA repair
double-strand break repair
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
tyrosyl-DNA phosphodiesterase
Functional Category
  • C: Energy production and conversion
  • E: Amino acid transport and metabolism
  • T: Signal transduction mechanisms
Displaying 1 entry
Gene Ontology
DNA repair
Displaying 1 entry
InterPro
Tyrosyl-DNA phosphodiesterase I
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0090115 spinocerebellar ataxia with axonal neuropathy 1
Ortholog
Displaying entries 1 - 10 of 89 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
55775 Xenbase:XB-GENE-950568
104884 MOUSE08667
314380 RATNO36178
453096 PANTR09341
490828 CANLF18160
517053 BOVIN01862
571485 DANRE12561
695338 MACMU41093
100015515 MONDO05599
100075184 ORNAN12874
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025