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MIRAGE
protein kinase C alpha
Summary
- Gene Symbol
-
- PRKCA
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Angiogenesis
- Apoptosis
- Calcium
- Cell adhesion
- Cell membrane
- Cytoplasm
- Direct protein sequencing
- Metal-binding
- Mitochondrion
- Nucleus
- Phosphoprotein
- Proteomics identification
- Proto-oncogene
- Reference proteome
- Repeat
- Serine/threonine-protein kinase
- Zinc
- Zinc-finger
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis | ||
| positive regulation of endothelial cell proliferation | ||
| desmosome assembly | ||
| chromatin remodeling | ||
| protein phosphorylation |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytosol | ||
| cytosol | ||
| plasma membrane | ||
| plasma membrane | ||
| mitochondrial membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase activity | ||
| protein serine/threonine kinase activity | ||
| diacylglycerol-dependent serine/threonine kinase activity | ||
| diacylglycerol-dependent serine/threonine kinase activity | ||
| calcium,diacylglycerol-dependent serine/threonine kinase activity |
GO Hierarchy
molecular function
catalytic activity [inference]
transferase activity [inference]
transferase activity, transferring phosphorus-containing groups [inference]
kinase activity [inference]
phosphotransferase activity, alcohol group as acceptor [inference]
catalytic activity, acting on a protein [inference]
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- protein kinase C
- Functional Category
-
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| ATP binding |
| kinase activity |
| metal ion binding |
| nucleotide binding |
| phosphorylation |
| transferase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10286 | prostate carcinoma | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:2394 | ovarian cancer | |
| DOID:3070 | high grade glioma | |
| DOID:3774 | chordoid glioma | |
| DOID:4552 | large cell carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 24680 | RATNO02287 | ||
| 24681 | SGD:S000000201 | ||
| 25023 | SGD:S000000201 | ||
| 25522 | SGD:S000000201 | ||
| 29340 | SGD:S000000201 | ||
| 29941 | SGD:S000000201 | ||
| 170538 | SGD:S000000201 | ||
| 181166 | Xenbase:XB-GENE-5942870 | ||
| 282001 | BOVIN14130 | ||
| 320795 | SGD:S000000201 |
