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MIRAGE
VPS11 core subunit of CORVET and HOPS complexes
Summary
- Gene Symbol
-
- VPS11
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Acetylation
- Autophagy
- Coiled coil
- Cytoplasmic vesicle
- Disease variant
- Dystonia
- Endosome
- Leukodystrophy
- Lysosome
- Membrane
- Methylation
- Nucleotide-binding
- Phosphoprotein
- Protein transport
- Proteomics identification
- Reference proteome
- Repeat
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A087WXL6 |
|
| B7Z879 |
|
| Q9H270 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular protein transport | ||
| vesicle docking involved in exocytosis | ||
| autophagy | ||
| endosome organization | ||
| vacuole organization |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleotide binding | ||
| protein binding | ||
| zinc ion binding | ||
| protein domain specific binding | ||
| syntaxin binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Vacuolar protein
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| endosome organization |
| metal ion binding |
| organelle fusion |
| protein-macromolecule adaptor activity |
| vesicle docking involved in exocytosis |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060796 | hypomyelinating leukodystrophy 12 | |
| DOID:0060939 | dystonia 32 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 55823 | Xenbase:XB-GENE-922526 | ||
| 71732 | MOUSE62504 | ||
| 315600 | RATNO40686 | ||
| 451601 | PANTR04526 | ||
| 489374 | CANLF15209 | ||
| 540381 | BOVIN06591 | ||
| 565852 | DANRE00609 | ||
| 702834 | MACMU08993 | ||
| 100024739 | MONDO24229 | ||
| 100089345 | ORNAN01954 |
