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solute carrier family 2, (facilitated glucose transporter), member 8

Summary

Gene Symbol

Slc2a8

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56017

PubChem

56017

Alliance of Genome Resources

MGI:1860103

Annotation

Keyword

Cell membrane
Cytoplasmic vesicle
Glycoprotein
Reference proteome
Sugar transport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JIF3	Glucose transporter type 8 Glucose transporter type X1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
response to hypoxia	IDA	11689004
glucose metabolic process	TAS	11689004
insulin receptor signaling pathway	IDA	10860996
fructose transmembrane transport	ISO	10671487
fructose transmembrane transport	IDA	23396969

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

glucose metabolic process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

localization [inference]

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

dehydroascorbic acid transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

organic substance transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

organic anion transport [inference]

dehydroascorbic acid transport

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

insulin receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	10821868
synaptic vesicle	ISO
membrane	IBA
cytoplasmic vesicle membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
fructose transmembrane transporter activity	IDA	23396969
galactose transmembrane transporter activity	ISO	10671487
glucose transmembrane transporter activity
glucose binding	IDA	10821868
fructose uniporter activity	ISO	10671487

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

carbohydrate transmembrane transporter activity [inference]

sugar transmembrane transporter activity [inference]

monosaccharide transmembrane transporter activity [inference]

hexose transmembrane transporter activity [inference]

fructose transmembrane transporter activity

fructose uniporter activity

galactose transmembrane transporter activity

glucose transmembrane transporter activity

D-glucose transmembrane transporter activity

hexose uniporter activity [inference]

fructose uniporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

uniporter activity [inference]

hexose uniporter activity [inference]

fructose uniporter activity

vitamin transmembrane transporter activity [inference]

dehydroascorbic acid transmembrane transporter activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

glucose binding

small molecule binding [inference]

monosaccharide binding [inference]

glucose binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transporter

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
InterPro
MFS transporter superfamily
Major facilitator superfamily domain
Major facilitator, sugar transporter-like
Sugar transporter, conserved site
Sugar/inositol transporter

Ortholog

Displaying entries **1 - 10** of 91 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	11182	FB:FBgn0028560
Homo sapiens	29988	Xenbase:XB-GENE-492572	HUMAN98489
Xenopus tropicalis	36248	Xenbase:XB-GENE-492572
Xenopus tropicalis	36249	Xenbase:XB-GENE-492572
Xenopus tropicalis	56017	Xenbase:XB-GENE-492572
Xenopus tropicalis	85256	Xenbase:XB-GENE-492572
Drosophila melanogaster	175458	FB:FBgn0050035
Drosophila melanogaster	180206	FB:FBgn0050035
Drosophila melanogaster	227659	FB:FBgn0034247
Danio rerio	373140		DANRE35955