GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein kinase activity	TAS	10570282
protein serine/threonine kinase activity	TAS
MAP kinase kinase activity	IDA	28166211 8388392
MAP kinase kinase activity	IBA
protein serine/threonine/tyrosine kinase activity	TAS	19565474

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

MAP kinase kinase activity

JUN kinase kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

MAP kinase kinase activity

JUN kinase kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

protein serine/threonine/tyrosine kinase activity

MAP kinase kinase activity

JUN kinase kinase activity

binding [inference]

protein binding

scaffold protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

signaling adaptor activity [inference]

MAP-kinase scaffold activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity

protein serine/threonine kinase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

dual specificity mitogen-activated

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
protein phosphorylation
transferase activity

Displaying **all 4** entries
InterPro
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0111462	cardiofaciocutaneous syndrome 3	Alliance of Genome Resources
DOID:3070	high grade glioma	Alliance of Genome Resources
DOID:4074	pancreatic adenocarcinoma	Alliance of Genome Resources
DOID:4253	melorheostosis	Alliance of Genome Resources
DOID:4450	renal cell carcinoma	Alliance of Genome Resources
DOID:4906	small intestine adenocarcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	5604	Xenbase:XB-GENE-478822
Saccharomyces cerevisiae S288C	5605	SGD:S000002318
Mus musculus	26395	Xenbase:XB-GENE-478822	MOUSE63301
Saccharomyces cerevisiae S288C	58960	SGD:S000002318
Rattus norvegicus	170851		RATNO42248
Danio rerio	406728		DANRE13583
Pan troglodytes	450188		PANTR10617
Canis lupus familiaris	478347		CANLF12622
Bos taurus	533199		BOVIN00495
Macaca mulatta	710415		MACMU41612

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements