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Repository for lectin-assisted multimodality data

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Tools

Glycan Converters

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Search Tools

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Guidelines

MIRAGE

catechol-O-methyltransferase a

Summary

Gene Symbol

comta

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

561372

PubChem

561372

Alliance of Genome Resources

ZFIN:ZDB-GENE-050913-117

Annotation

Keyword

Alternative splicing
Catecholamine metabolism
Glycoprotein
Magnesium
Metal-binding
Methyltransferase
Neurotransmitter degradation
Reference proteome
S-adenosyl-L-methionine
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
F4ZGF2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
catecholamine metabolic process	IEA
methylation	IEA
developmental process	IBA
dopamine metabolic process	IBA
catecholamine catabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

developmental process

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
methyltransferase activity	IEA
O-methyltransferase activity	IEA
catechol O-methyltransferase activity	IDA	21371608
catechol O-methyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity

O-methyltransferase activity

catechol O-methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

catechol O-methyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

magnesium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

O methyltransferase

Functional Category

G: Carbohydrate transport and metabolism
H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 6** entries
Gene Ontology
O-methyltransferase activity
catecholamine catabolic process
catecholamine metabolic process
dopamine metabolic process
methylation
transferase activity

Displaying **all 2** entries
InterPro
Class I-like SAM-dependent O-methyltransferase
S-adenosyl-L-methionine-dependent methyltransferase superfamily

Ortholog

Displaying entries **1 - 10** of 59 in total

1

2

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5

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1312	Xenbase:XB-GENE-5865481	HUMAN59230
Mus musculus	12846	Xenbase:XB-GENE-948947	MOUSE19552
Rattus norvegicus	24267	Xenbase:XB-GENE-948947	RATNO04095
Canis lupus familiaris	445450		CANLF10595
Pan troglodytes	458655		PANTR25982
Xenopus tropicalis	561372	Xenbase:XB-GENE-5865481
Homo sapiens	565370	HGNC:2228
Macaca mulatta	712548		MACMU00872
Sus scrofa	100155530		PIGXX07450
Taeniopygia guttata	100223814		TAEGU05974

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025