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glycerophosphodiester phosphodiesterase 1

Summary

Gene Symbol

Gde1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56209

PubChem

56209

Alliance of Genome Resources

MGI:1891827

Annotation

Keyword

Cell membrane
Cytoplasmic vesicle
Glycoprotein
Hydrolase
Lipid metabolism
Magnesium
Metal-binding
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JL56	Glycerophosphoinositol glycerophosphodiesterase GDE1 Lysophospholipase D GDE1 Membrane-interacting protein of RGS16

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
ethanolamine metabolic process	IMP	18227059
ethanolamine metabolic process	IBA
phospholipid metabolic process	IDA	25596343
phospholipid metabolic process	IBA
G protein-coupled receptor signaling pathway	ISO	10760272

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

ethanolamine-containing compound metabolic process [inference]

primary amino compound metabolic process [inference]

ethanolamine metabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanolamine-containing compound metabolic process [inference]

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

ethanolamine-containing compound metabolic process [inference]

primary amino compound metabolic process [inference]

ethanolamine metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

ethanolamine-containing compound metabolic process [inference]

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	ISS	10760272
plasma membrane	IMP	18227059
plasma membrane	IBA
membrane	IDA	25596343
cytoplasmic vesicle membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
lysophospholipase activity	IDA	25596343
phosphoric diester hydrolase activity	IDA	25596343
glycerophosphodiester phosphodiesterase activity	ISS	10760272
glycerophosphodiester phosphodiesterase activity	IMP	21801852
glycerophosphodiester phosphodiesterase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

lysophospholipase activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity

carboxylic ester hydrolase activity [inference]

lysophospholipase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Glycerophosphodiester phosphodiesterase

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
N-acylethanolamine metabolic process
lipid metabolic process

Displaying **all 2** entries
InterPro
Glycerophosphodiester phosphodiesterase domain
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily

Rhea

RHEA:16501

H₂O + sn-glycero-3-phospho-1D-myo-inositol

H⁺ + myo-inositol + sn-glycerol 3-phosphate

Enzyme

3.1.4.44

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006077
Gene Name: glycerophosphodiester phosphodiesterase 1

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	51573	Xenbase:XB-GENE-976293	HUMAN26975
Xenopus tropicalis	56209	Xenbase:XB-GENE-976293
Xenopus tropicalis	60418	Xenbase:XB-GENE-976293
Danio rerio	393213		DANRE22182
Pan troglodytes	453968		PANTR11868
Canis lupus familiaris	479827		CANLF16527
Bos taurus	539978		BOVIN20363
Macaca mulatta	694849		MACMU26872
Monodelphis domestica	100018844		MONDO28958
Equus caballus	100050012		HORSE07677

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements