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Guidelines

MIRAGE

glycerophosphocholine phosphodiesterase 1

Summary

Gene Symbol

GPCPD1

Aliases

GDE5
GDPD6
KIAA1434

Organism

Homo sapiens (human)

External Links

NCBI Gene

56261

HGNC

26957

KEGG Gene ID

hsa:56261

PubChem

56261

Alliance of Genome Resources

HGNC:26957

Annotation

Keyword

3D-structure
Cytoplasm
Hydrolase
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NPB8	Glycerophosphodiester phosphodiesterase 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
skeletal muscle tissue development	IEA
glycerophospholipid catabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

glycerophospholipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

muscle tissue development [inference]

skeletal muscle tissue development

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	28514442 33961781
glycerophosphocholine phosphodiesterase activity	IBA
starch binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

glycerophosphocholine phosphodiesterase activity

binding [inference]

protein binding

carbohydrate binding [inference]

polysaccharide binding [inference]

starch binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

glycerophosphocholine phosphodiesterase

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
glycerophosphocholine phosphodiesterase activity
glycerophospholipid catabolic process
lipid metabolic process

Displaying **all 2** entries
InterPro
Glycerophosphodiester phosphodiesterase domain
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily

KEGG BRITE Database

Orthology

K18695

Name

glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2]

References

20576599

Rhea

H₂O + sn-glycerol 3-phosphocholine

choline + H⁺ + sn-glycerol 3-phosphate

Enzyme

3.1.4.2

PMID

Ortholog

Displaying entries **21 - 30** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Loxodonta africana	100661261		LOXAF12945
Cavia porcellus	100713039		CAVPO04722
Sarcophilus harrisii	100923561		SARHA19226
Otolemur garnettii	100942596		OTOGA13401
Pan paniscus	100992325		PANPA21816
Saimiri boliviensis boliviensis	101052158		SAIBB21842
Takifugu rubripes	101064928		TAKRU13900
Felis catus	101081213		FELCA07649
Ovis aries	101115143		SHEEP04356
Gorilla gorilla gorilla	101144579		GORGO22781

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025