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gamma-glutamyl carboxylase

Summary

Gene Symbol

Ggcx

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56316

PubChem

56316

Alliance of Genome Resources

MGI:1927655

Annotation

Keyword

Acetylation
Disulfide bond
Endoplasmic reticulum
Lipid-binding
Lyase
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2RS80	Gamma-glutamyl carboxylase Peptidyl-glutamate 4-carboxylase Vitamin K gamma glutamyl carboxylase
Q9QYC7	Gamma-glutamyl carboxylase Peptidyl-glutamate 4-carboxylase Vitamin K gamma glutamyl carboxylase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
peptidyl-glutamic acid carboxylation	IMP	17327402
vitamin K metabolic process	ISO
vitamin K metabolic process	IMP	37171959
vitamin K metabolic process	IBA
negative regulation of neurotransmitter secretion	IMP	25264202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-glutamic acid modification [inference]

peptidyl-glutamic acid carboxylation

protein carboxylation [inference]

peptidyl-glutamic acid carboxylation

protein maturation

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

vitamin K metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-glutamic acid modification [inference]

peptidyl-glutamic acid carboxylation

protein carboxylation [inference]

peptidyl-glutamic acid carboxylation

protein maturation

small molecule metabolic process [inference]

vitamin metabolic process [inference]

fat-soluble vitamin metabolic process [inference]

vitamin K metabolic process

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

vitamin K metabolic process

organic substance metabolic process [inference]

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

vitamin K metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-glutamic acid modification [inference]

peptidyl-glutamic acid carboxylation

protein carboxylation [inference]

peptidyl-glutamic acid carboxylation

protein maturation

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-glutamic acid modification [inference]

peptidyl-glutamic acid carboxylation

protein carboxylation [inference]

peptidyl-glutamic acid carboxylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-glutamic acid modification [inference]

peptidyl-glutamic acid carboxylation

protein carboxylation [inference]

peptidyl-glutamic acid carboxylation

protein maturation

cellular process [inference]

cellular metabolic process [inference]

cellular ketone metabolic process [inference]

quinone metabolic process [inference]

vitamin K metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of small molecule metabolic process [inference]

negative regulation of testosterone biosynthetic process

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of small molecule metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of small molecule metabolic process [inference]

negative regulation of testosterone biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of steroid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of lipid biosynthetic process [inference]

regulation of steroid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid metabolic process [inference]

negative regulation of steroid metabolic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of lipid biosynthetic process [inference]

negative regulation of steroid biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of small molecule metabolic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

negative regulation of neurotransmitter transport [inference]

negative regulation of neurotransmitter secretion

negative regulation of developmental process [inference]

negative regulation of bone development

negative regulation of multicellular organismal process [inference]

negative regulation of bone development

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of bone development

regulation of multicellular organismal development [inference]

regulation of bone development [inference]

negative regulation of bone development

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

regulation of cellular metabolic process [inference]

regulation of cellular ketone metabolic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of ketone biosynthetic process [inference]

regulation of testosterone biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of testosterone biosynthetic process

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion [inference]

negative regulation of neurotransmitter secretion

negative regulation of secretion by cell [inference]

negative regulation of neurotransmitter secretion

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of bone development

regulation of multicellular organismal development [inference]

regulation of bone development [inference]

negative regulation of bone development

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IDA	17327402
endoplasmic reticulum membrane	ISO
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
gamma-glutamyl carboxylase activity	ISS	10893417
gamma-glutamyl carboxylase activity	ISO
gamma-glutamyl carboxylase activity	IDA	25264202
gamma-glutamyl carboxylase activity	IMP	17327402 25264202
gamma-glutamyl carboxylase activity	IBA