GlyCosmos Portal

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
Glycoprotein
Hydrolase
Lipid metabolism
Lysosome
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8CE08	5'-nucleotidase Acid phosphatase 3 Ecto-5'-nucleotidase Fluoride-resistant acid phosphatase Protein tyrosine phosphatase ACP3 Thiamine monophosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
purine nucleobase metabolic process	IMP	18940592
chromatin remodeling	IEA
lipid metabolic process	IEA
thiamine metabolic process	IMP	18940592
nucleotide metabolic process	IMP	18940592

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

dephosphorylation

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

lipid metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

organic substance metabolic process [inference]

lipid metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

carbohydrate derivative metabolic process [inference]

glycosyl compound metabolic process [inference]

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

thiamine metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

dephosphorylation

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process

nucleobase metabolic process [inference]

purine nucleobase metabolic process

nucleoside metabolic process [inference]

ribonucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

purine nucleoside metabolic process [inference]

purine ribonucleoside metabolic process [inference]

adenosine metabolic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process [inference]

thiamine metabolic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

regulation of adenosine receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

regulation of adenosine receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

regulation of adenosine receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of G protein-coupled receptor signaling pathway [inference]

positive regulation of adenosine receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

regulation of sensory perception [inference]

regulation of sensory perception of pain

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
extracellular space	ISS
extracellular space	ISO
lysosomal membrane	IEA
multivesicular body	ISO
multivesicular body	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

Golgi cisterna

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

secretory vesicle [inference]

secretory granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

secretory vesicle [inference]

secretory granule

apical part of cell

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
acid phosphatase activity	ISS	2373368
acid phosphatase activity	ISO
protein tyrosine phosphatase activity
non-membrane spanning protein tyrosine phosphatase activity	IEA
5'-nucleotidase activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity

acid phosphatase activity

thiamine phosphate phosphatase activity

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

nucleotidase activity [inference]

5'-nucleotidase activity

XMP 5'-nucleosidase activity

lysophosphatidic acid phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding [inference]

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

ion binding [inference]

cation binding [inference]

choline binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Phosphatase

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
dephosphorylation

Displaying **all 2** entries
InterPro
Histidine phosphatase superfamily, clade-2
Histidine phosphatase superfamily

Rhea

RHEA:12484

H₂O + a ribonucleoside 5'-phosphate

a ribonucleoside + phosphate

Enzyme

3.1.3.5

PMID

RHEA:15017

H₂O + a phosphate monoester

an alcohol + phosphate

Enzyme

PMID

RHEA:10684

H₂O

phosphate

Enzyme

3.1.3.48

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10283	prostate cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	53	FB:FBgn0038912
Homo sapiens	55	HGNC:125	HUMAN72319
Drosophila melanogaster	11432	FB:FBgn0038912
Homo sapiens	56318	HGNC:125
Rattus norvegicus	56780	HGNC:125	RATNO42042
Drosophila melanogaster	93650	FB:FBgn0038912
Homo sapiens	176030	HGNC:125
Drosophila melanogaster	179621	FB:FBgn0036877
Drosophila melanogaster	188683	FB:FBgn0000032
Pan troglodytes	460702		PANTR32201

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OrthoDB (Group)

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Acknowledgements