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PDZ and LIM domain 5

Summary

Gene Symbol

Pdlim5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56376

PubChem

56376

Alliance of Genome Resources

MGI:1927489

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cell projection
Cytoplasm
Isopeptide bond
LIM domain
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Synapse
Ubl conjugation

Proteins

Displaying **all 8** entries
UniProt	Protein Name
D9J301
Q9CRA2
E9Q8P5
D9J302
Q8CI51	Enigma homolog Enigma-like PDZ and LIM domains protein
D9J303
D9J300
D9J2Z9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
actin cytoskeleton organization	IBA
heart development	IBA
muscle structure development	IBA
regulation of synapse assembly	ISO ISS
cell growth involved in cardiac muscle cell development	ISO

GO Hierarchy

biological process

cellular process [inference]

cell growth [inference]

developmental cell growth [inference]

cell growth involved in cardiac muscle cell development

actin filament-based process [inference]

actin cytoskeleton organization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

heart development

muscle structure development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

cell growth involved in cardiac muscle cell development

developmental growth [inference]

developmental cell growth [inference]

cell growth involved in cardiac muscle cell development

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendritic spine morphogenesis

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of dendritic spine morphogenesis

regulation of synapse organization [inference]

regulation of synapse assembly

regulation of postsynapse organization [inference]

regulation of dendritic spine morphogenesis

regulation of cell junction assembly [inference]

regulation of synapse assembly

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GO Term	Evidence Code	PMID
membrane	ISO
postsynaptic density	ISO ISS
presynapse	IEA
filamentous actin	IBA
cell projection	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

filamentous actin

cellular anatomical entity [inference]

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

cell projection

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

postsynaptic specialization [inference]

postsynaptic density

presynapse

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	10833443
actin binding	IBA ISO
actinin binding	ISO
metal ion binding	IEA
muscle alpha-actinin binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding

actinin binding

alpha-actinin binding [inference]

muscle alpha-actinin binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

PDZ and LIM domain protein 5

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 5** entries
Gene Ontology
actin binding
actin cytoskeleton organization
metal ion binding
muscle alpha-actinin binding
muscle structure development

Displaying **all 3** entries
InterPro
PDZ domain
PDZ superfamily
Zinc finger, LIM-type

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050700	cardiomyopathy	Alliance of Genome Resources
DOID:0080095	myofibrillar myopathy 4	Alliance of Genome Resources
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:423	myopathy	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of **106** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Loxodonta africana	100665701		LOXAF10303
Oreochromis niloticus	100690021		ORENI11685
Oreochromis niloticus	100698484		ORENI11685
Cavia porcellus	100732952	10141_0:002e34	CAVPO10820
Cricetulus griseus	100770600	10029_0:000649
Otolemur garnettii	100953710		OTOGA04650
Saimiri boliviensis boliviensis	101048220		SAIBB16010
Ovis aries	101114358		SHEEP17219
Oryzias latipes	101174195		ORYLA17515
Tursiops truncatus	101321063		TURTR12619

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements