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syntaxin 5A

Summary

Gene Symbol

Stx5a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56389

PubChem

56389

Alliance of Genome Resources

MGI:1928483

Annotation

Keyword

Alternative initiation
Coiled coil
Golgi apparatus
Reference proteome
Transmembrane helix
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K1E0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 13** of 13 in total

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GO Term	Evidence Code	PMID
positive regulation of protein catabolic process	ISO
early endosome to Golgi transport	ISO
Golgi disassembly	ISO

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

Golgi vesicle transport [inference]

membrane docking [inference]

organelle localization by membrane tethering [inference]

vesicle docking

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

Golgi organization [inference]

vesicle organization [inference]

vesicle fusion with Golgi apparatus

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion with Golgi apparatus

organelle disassembly [inference]

Golgi disassembly

cellular component disassembly [inference]

organelle disassembly [inference]

Golgi disassembly

membrane organization [inference]

membrane fusion

organelle membrane fusion [inference]

vesicle fusion with Golgi apparatus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

Golgi vesicle transport [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

organelle localization [inference]

organelle localization by membrane tethering [inference]

vesicle docking

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of cellular process [inference]

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of Golgi organization

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
endoplasmic reticulum-Golgi intermediate compartment membrane	IEA
Golgi apparatus	ISO
vesicle	ISO
Golgi membrane	IBA ISO TAS	9094723
endomembrane system	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

SNARE complex

cellular anatomical entity [inference]

endomembrane system

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 2** entries
GO Term	Evidence Code	PMID
SNAP receptor activity	IBA IEA ISO
SNARE binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

SNARE binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

SNAP receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Syntaxin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism

Displaying **all 3** entries
Gene Ontology
SNARE binding
vesicle docking
vesicle fusion

Displaying **all 5** entries
InterPro
SNARE
Syntaxin-5, N-terminal, Sly1p-binding domain
Syntaxin/epimorphin, conserved site
Syntaxin
Target SNARE coiled-coil homology domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050571	congenital disorder of glycosylation type II	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of **114** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Macaca mulatta	718435			MACMU10904
Saccharomyces cerevisiae S288C	850713		SGD:S000004016
Ornithorhynchus anatinus	100077755			ORNAN17069
Salmo salar	100194741			SALSA14838
Callithrix jacchus	100400080			CALJA05038
Pongo abelii	100448467			PONAB02452
Ailuropoda melanoleuca	100481696			AILME06440
Nomascus leucogenys	100583207			NOMLE30017
Sus scrofa	100628048			PIGXX16960
Loxodonta africana	100674947			LOXAF04972

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Last updated: December 9, 2024