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MIRAGE
NAD-protein-arginine ADP-ribosyltransferase
Summary
- Gene Symbol
-
- SIR2RP1
- Organism
- Leishmania major strain Friedlin
Annotation
- Keyword
-
- Metal-binding
- NAD
- Nucleus
- Reference proteome
- Repressor
- Transcription regulation
- Transferase
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| Q25337 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| DNA repair |
|
|
| B cell activation |
|
|
| macrophage activation |
|
|
| perturbation of host innate immune response |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus |
|
|
| cytosol |
|
|
| cytoskeleton |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| NAD+ ADP-ribosyltransferase activity |
|
|
| histone deacetylase activity |
|
|
| NAD-dependent histone deacetylase activity | ||
| NAD-dependent protein deacetylase activity |
|
|
| tubulin deacetylase activity |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- NAD-dependent protein deacetylase
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| NAD+ binding |
| NAD-dependent histone deacetylase activity |
| metal ion binding |
| transferase activity |
| InterPro |
|---|
| DHS-like NAD/FAD-binding domain superfamily |
| Sirtuin family, catalytic core domain |
| Sirtuin family |
| Sirtuin, catalytic core small domain superfamily |
Rhea
