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deoxyribonuclease II beta

Summary

Gene Symbol

Dnase2b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56629

PubChem

56629

Alliance of Genome Resources

MGI:1913283

Annotation

Keyword

Endonuclease
Glycoprotein
Lysosome
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QY48	DNase II-like acid DNase DNase2-like acid DNase Deoxyribonuclease II beta Endonuclease DLAD

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
DNA metabolic process	IEA
apoptotic DNA fragmentation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasm	IDA	10497274
extracellular region	IDA	10497274
lysosome	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
DNA endonuclease activity	IDA	10497274
endodeoxyribonuclease activity	IDA	10497274
deoxyribonuclease II activity	IBA IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

endodeoxyribonuclease activity

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [inference]

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

DNA nuclease activity [inference]

endodeoxyribonuclease activity

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

endodeoxyribonuclease activity

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:83	cataract	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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