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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sphingosine kinase 2
Summary
- Gene Symbol
-
- SPHK2
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of reactive oxygen species biosynthetic process | ||
| sphingolipid biosynthetic process |
|
GO Hierarchy
- regulation of reactive oxygen species biosynthetic process
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| intracellular membrane-bounded organelle | ||
| endoplasmic reticulum | ||
| mitochondrial inner membrane | ||
| nucleosome |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| small GTPase binding |
|
|
| D-erythro-sphingosine kinase activity | ||
| histone binding | ||
| lipid kinase activity |
|
|
| sphinganine kinase activity |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:6811 | juvenile pilocytic astrocytoma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:686 | liver carcinoma | |
| DOID:7005 | gemistocytic astrocytoma | |
| DOID:7007 | childhood cerebral astrocytoma | |
| DOID:7008 | protoplasmic astrocytoma | |
| DOID:7148 | rheumatoid arthritis | |
| DOID:7474 | malignant pleural mesothelioma | |
| DOID:769 | neuroblastoma | |
| DOID:784 | chronic kidney disease |
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP001959
- Gene Name
- sphingosine kinase 2
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 129528634 | GORGO16971 | ||
| 100992056 | PANPA20946 | ||
| 112931373 | VULVU26894 | ||
| 123776264 | URSAM26321 | ||
| 100479407 | AILME14193 | ||
| 101672769 | MUSPF06934 | ||
| 101081345 | FELCA33760 | ||
| 122207917 | PANLE29379 | ||
| 118884818 | BALMU16273 | ||
| 100676401 | LOXAF18122 |
