GlyCosmos Portal

Annotation

Keyword

Acetylation
Alternative splicing
Golgi apparatus
Magnesium
Manganese
Metal-binding
Phospholipid biosynthesis
Reference proteome
Transferase
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8WUD6	AAPT1-like protein Diacylglycerol cholinephosphotransferase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
regulation of cell growth	NAS	10893425
lipid metabolic process	TAS	10893425
phosphatidylcholine biosynthetic process	IDA	10893425
CDP-choline pathway	NAS	10893425
platelet activating factor biosynthetic process	IDA	10893425

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

primary metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

small molecule metabolic process [inference]

ether metabolic process [inference]

glycerol ether metabolic process [inference]

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

ether metabolic process [inference]

glycerol ether metabolic process [inference]

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organonitrogen compound metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether biosynthetic process [inference]

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

organonitrogen compound biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerol ether biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

phospholipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

ether lipid metabolic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

platelet activating factor metabolic process [inference]

platelet activating factor biosynthetic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

glycerolipid biosynthetic process [inference]

glycerophospholipid biosynthetic process [inference]

phosphatidylcholine biosynthetic process

CDP-choline pathway

platelet activating factor biosynthetic process

cellular lipid biosynthetic process [inference]

ether lipid biosynthetic process [inference]

platelet activating factor biosynthetic process

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of cell growth

regulation of cellular process [inference]

regulation of cellular component organization [inference]

regulation of cell growth

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IDA	12221122
endoplasmic reticulum membrane	IBA
Golgi apparatus	IBA
membrane	NAS	10893425

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
diacylglycerol cholinephosphotransferase activity	IDA	10893425
diacylglycerol cholinephosphotransferase activity	IBA
protein binding	IPI	32296183
diacylglycerol binding	NAS	10893425
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

phosphotransferase activity, for other substituted phosphate groups [inference]

CDP-alcohol phosphatidyltransferase activity [inference]

diacylglycerol cholinephosphotransferase activity

binding [inference]

protein binding

lipid binding [inference]

diacylglycerol binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cholinephosphotransferase

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 6** entries
Gene Ontology
diacylglycerol cholinephosphotransferase activity
ethanolaminephosphotransferase activity
phosphatidylethanolamine biosynthetic process
phospholipid biosynthetic process
phosphotransferase activity, for other substituted phosphate groups
transferase activity

Displaying **all 4** entries
InterPro
CDP-alcohol phosphatidyltransferase, conserved site
CDP-alcohol phosphatidyltransferase, transmembrane domain
CDP-alcohol phosphatidyltransferase
Choline/ethanolamine phosphotransferase

Rhea

RHEA:32939

a 1,2-diacyl-sn-glycerol + CDP-choline

H⁺ + a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP

Enzyme

2.7.8.2

PMID

RHEA:36183

a 1-O-alkyl-2-acetyl-sn-glycerol + CDP-choline

H⁺ + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CMP

Enzyme

2.7.8.2

RHEA:36179

1-O-alkyl-2-acyl-sn-glycerol + CDP-choline

H⁺ + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CMP

Enzyme

2.7.8.2

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006641
Gene Name: choline phosphotransferase 1

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	10390	SGD:S000001165
Xenopus tropicalis	56994	Xenbase:XB-GENE-973251
Saccharomyces cerevisiae S288C	85465	SGD:S000005074
Saccharomyces cerevisiae S288C	99712	SGD:S000001165
Mus musculus	212862		MOUSE00354
Saccharomyces cerevisiae S288C	310773	SGD:S000001165
Danio rerio	322605		DANRE32864
Rattus norvegicus	362866		RATNO38289
Pan troglodytes	467109		PANTR06706
Saccharomyces cerevisiae S288C	549188	SGD:S000005074

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements