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coenzyme Q9

Summary

Gene Symbol

COQ9

Organism

Homo sapiens (human)

External Links

NCBI Gene

57017

PubChem

57017

Alliance of Genome Resources

HGNC:25302

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Lipid-binding
Mitochondrion
Primary mitochondrial disease
Reference proteome
Transit peptide
Ubiquinone biosynthesis
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
O75208

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
ubiquinone biosynthetic process	IBA IEA ISS NAS	28927698
mitochondrial electron transport, NADH to ubiquinone	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

organic substance biosynthetic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

cellular ketone metabolic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

quinone metabolic process [inference]

ubiquinone metabolic process [inference]

ubiquinone biosynthetic process

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

cellular biosynthetic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

small molecule metabolic process [inference]

cellular ketone metabolic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

quinone metabolic process [inference]

ubiquinone metabolic process [inference]

ubiquinone biosynthetic process

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

small molecule biosynthetic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

organic substance metabolic process [inference]

cellular ketone metabolic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

quinone metabolic process [inference]

ubiquinone metabolic process [inference]

ubiquinone biosynthetic process

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

organic substance biosynthetic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

cellular respiration [inference]

aerobic respiration [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

electron transport chain [inference]

respiratory electron transport chain [inference]

aerobic electron transport chain [inference]

mitochondrial electron transport, NADH to ubiquinone

cellular ketone metabolic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

quinone metabolic process [inference]

ubiquinone metabolic process [inference]

ubiquinone biosynthetic process

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

cellular biosynthetic process [inference]

ketone biosynthetic process [inference]

quinone biosynthetic process [inference]

ubiquinone biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrial inner membrane	IBA IDA TAS	27499296
ubiquinone biosynthesis complex	IPI	27499296
mitochondrion	HDA HTP	20833797 34800366

GO Hierarchy

cellular component

protein-containing complex [inference]

ubiquinone biosynthesis complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25339443 27499296 32296183
lipid binding	IBA IDA	25339443
protein homodimerization activity	IDA	25339443

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

acyltransferase

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050730	coenzyme Q10 deficiency disease	Alliance of Genome Resources
DOID:0070242	primary coenzyme Q10 deficiency 5	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 75 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Oryzias latipes	101167533			ORYLA15263
Tursiops truncatus	101325542			TURTR10990
Octodon degus	101568748			OCTDE03681
Jaculus jaculus	101611655			JACJA22792
Mustela putorius furo	101688239			MUSPF16883
Heterocephalus glaber	101710528			HETGA17169
Ficedula albicollis	101819303			FICAL04550
Melopsittacus undulatus	101879835			MELUD03702
Chrysemys picta bellii	101947373			CHRPI27735
Ictidomys tridecemlineatus	101957194			ICTTR11766

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024