GlyCosmos Portal

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GO Term	Evidence Code	PMID
RNA binding	HDA	22681889
arginine-tRNA ligase activity	TAS
arginine-tRNA ligase activity	IMP	17847012
arginine-tRNA ligase activity	IBA
protein binding	IPI	32814053

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-oxygen bonds [inference]

aminoacyl-tRNA ligase activity [inference]

arginine-tRNA ligase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

catalytic activity, acting on a tRNA [inference]

aminoacyl-tRNA ligase activity [inference]

arginine-tRNA ligase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

arginine--tRNA ligase

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
arginine-tRNA ligase activity
arginyl-tRNA aminoacylation
ligase activity
mitochondrial translation
nucleotide binding
tRNA aminoacylation for protein translation

Displaying **all 8** entries
InterPro
Aminoacyl-tRNA synthetase, class I, conserved site
Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
Arginine-tRNA ligase
Arginyl tRNA synthetase N-terminal domain superfamily
Arginyl tRNA synthetase N-terminal domain
Arginyl-tRNA synthetase, catalytic core domain
DALR anticodon binding
Rossmann-like alpha/beta/alpha sandwich fold

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060275	pontocerebellar hypoplasia type 6	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	57038	Xenbase:XB-GENE-976890
Mus musculus	109093		MOUSE42511
Rattus norvegicus	297969		RATNO32823
Danio rerio	393589		DANRE18666
Pan troglodytes	462875		PANTR38673
Canis lupus familiaris	481911		CANLF02971
Bos taurus	525894		BOVIN35716
Macaca mulatta	699240		MACMU34335
Monodelphis domestica	100019290		MONDO15123
Equus caballus	100070665		HORSE00866

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Acknowledgements