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notum, palmitoleoyl-protein carboxylesterase a

Summary

Gene Symbol

notum1a

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

570510

PubChem

570510

Alliance of Genome Resources

ZFIN:ZDB-GENE-120807-2

Annotation

Keyword

Glycoprotein
Reference proteome
Secreted
Serine esterase
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
C5H5C4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
GPI anchor release
anterior/posterior pattern specification	IMP	23293289
Wnt signaling pathway	IEA
neural tube patterning	IMP	22669824
negative regulation of Wnt signaling pathway	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

primary metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

macromolecule modification [inference]

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

macromolecule deacylation [inference]

protein deacylation [inference]

protein depalmitoleylation

carbohydrate derivative metabolic process [inference]

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

protein modification process [inference]

protein deacylation [inference]

protein depalmitoleylation

lipoprotein metabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

lipoprotein catabolic process [inference]

protein depalmitoleylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylinositol metabolic process [inference]

GPI anchor metabolic process [inference]

GPI anchor release

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway

negative regulation of canonical Wnt signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glycosylphosphatidylinositol phospholipase D activity	IDA	22669824
hydrolase activity	IEA
carboxylic ester hydrolase activity	IEA
palmitoleyl hydrolase activity	ISS
palmitoleyl hydrolase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

phospholipase activity [inference]

phospholipase D activity [inference]

glycosylphosphatidylinositol phospholipase D activity

phosphoric ester hydrolase activity [inference]

phosphoric diester hydrolase activity [inference]

phospholipase D activity [inference]

glycosylphosphatidylinositol phospholipase D activity

carboxylic ester hydrolase activity

palmitoleyl hydrolase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

PI-PLC X domain-containing protein

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
hydrolase activity

Displaying 1 entry
InterPro
Pectinacetylesterase/NOTUM

Ortholog

Displaying entries **1 - 10** of 63 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	39751	Xenbase:XB-GENE-996986
Mus musculus	77583	Xenbase:XB-GENE-996986	MOUSE05122
Homo sapiens	147111	Xenbase:XB-GENE-996986	HUMAN37145
Rattus norvegicus	303743		RATNO02096
Xenopus tropicalis	444338	Xenbase:XB-GENE-996986
Canis lupus familiaris	483374		CANLF18334
Drosophila melanogaster	566040	FB:FBgn0044028
Xenopus tropicalis	570510	Xenbase:XB-GENE-996986
Monodelphis domestica	100029923		MONDO11066
Ornithorhynchus anatinus	100079087		ORNAN00246