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integrator complex subunit 12

Summary

Gene Symbol

INTS12

Organism

Homo sapiens (human)

External Links

NCBI Gene

57117

PubChem

57117

Alliance of Genome Resources

HGNC:25067

Annotation

Keyword

Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96CB8	PHD finger protein 22

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
snRNA processing	NAS	16239144
snRNA processing	IDA	16239144
regulation of transcription elongation by RNA polymerase II	NAS	32697989
snRNA 3'-end processing	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

RNA 3'-end processing [inference]

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

ncRNA metabolic process [inference]

snRNA metabolic process [inference]

snRNA processing

snRNA 3'-end processing

ncRNA processing [inference]

snRNA processing

snRNA 3'-end processing

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-templated transcription elongation [inference]

regulation of transcription elongation by RNA polymerase II

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleus	NAS	32647223
nucleus	IDA	23904267 39032490
nucleoplasm	TAS
integrator complex	NAS	33548203
integrator complex	IDA	16239144 39032490

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

integrator complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16239144 26275350 28514442 32296183 33961781
zinc ion binding	IEA
metal ion binding

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrator complex subunit 12

Functional Category

C: Energy production and conversion
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
metal ion binding
snRNA 3'-end processing

Displaying **all 6** entries
InterPro
Int12, PHD finger
Zinc finger, FYVE/PHD-type
Zinc finger, PHD-finger
Zinc finger, PHD-type, conserved site
Zinc finger, PHD-type
Zinc finger, RING/FYVE/PHD-type

Ortholog

Displaying entries **1 - 10** of 92 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	57117	Xenbase:XB-GENE-977203
Mus musculus	71793		MOUSE37748
Rattus norvegicus	295448		RATNO23475
Danio rerio	415251		DANRE17320
Pan troglodytes	461418		PANTR34258
Canis lupus familiaris	487889		CANLF13127
Bos taurus	517489		BOVIN31113
Macaca mulatta	694344		MACMU37699
Monodelphis domestica	100011480		MONDO26239
Equus caballus	100064467		HORSE27406