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nucleoporin 107

Summary

Gene Symbol

NUP107

Organism

Homo sapiens (human)

External Links

NCBI Gene

57122

PubChem

57122

Alliance of Genome Resources

HGNC:29914

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Centromere
Chromosome
Disease variant
Epilepsy
Intellectual disability
Kinetochore
Membrane
Methylation
Nuclear pore complex
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P57740	107 kDa nucleoporin Nucleoporin Nup107

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery	IBA
mRNA export from nucleus	IDA	11684705
mRNA export from nucleus	IBA
protein import into nucleus	IBA
nucleocytoplasmic transport	NAS	27016207

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization [inference]

nuclear pore complex assembly

chromosome organization [inference]

transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery [inference]

post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery

cellular component assembly [inference]

protein-containing complex assembly [inference]

pore complex assembly [inference]

nuclear pore complex assembly

protein-containing complex organization [inference]

nuclear pore organization [inference]

nuclear pore complex assembly

protein-containing complex assembly [inference]

pore complex assembly [inference]

nuclear pore complex assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

anatomical structure development [inference]

animal organ development [inference]

gonad development [inference]

female gonad development

reproductive structure development [inference]

gonad development [inference]

female gonad development

nephron development

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

mRNA transport [inference]

mRNA export from nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus [inference]

mRNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
kinetochore	IDA	17363900
nuclear envelope	TAS
nuclear envelope	IDA	24315095
nuclear pore	NAS	24315095
nuclear pore	IDA	11564755 11684705 12802065 15229283 26411495

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

cytosol

membrane

organelle membrane [inference]

nuclear membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

nuclear periphery

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

supramolecular complex [inference]

kinetochore

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11564755 15146057 17363900 24407287 26411495 26496610 27194810 30179222 33961781 35271311
structural constituent of nuclear pore	IDA	11684705
structural constituent of nuclear pore	IMP	15229283
structural constituent of nuclear pore	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nuclear pore complex protein

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
mRNA export from nucleus
mRNA transport
post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
protein import into nucleus

Displaying 1 entry
InterPro
Nuclear pore protein 84/107

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080385	nephrotic syndrome type 11	Alliance of Genome Resources
DOID:0080498	ovarian dysgenesis 6	Alliance of Genome Resources
DOID:0080694	Galloway-Mowat syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 85 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	57122	Xenbase:XB-GENE-1006597
Mus musculus	103468	Xenbase:XB-GENE-1006597	MOUSE00104
Rattus norvegicus	116555		RATNO38000
Pan troglodytes	467062		PANTR06353
Canis lupus familiaris	474440		CANLF01406
Bos taurus	504823		BOVIN29457
Danio rerio	562350		DANRE33022
Macaca mulatta	718214		MACMU03841
Monodelphis domestica	100021491		MONDO34404
Equus caballus	100059287		HORSE36857