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frizzled class receptor 2

Summary

Gene Symbol

Fzd2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

57265

KEGG Gene ID

PubChem

57265

Alliance of Genome Resources

MGI:1888513

Annotation

Keyword

Cell membrane
Developmental protein
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix
Ubl conjugation
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JIP6	Frizzled-10

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 26 in total

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GO Term	Evidence Code	PMID
positive regulation of cytosolic calcium ion concentration	ISO
Wnt signaling pathway, calcium modulating pathway	ISO
cell-cell signaling	IDA
sensory perception of smell	IMP
Wnt signaling pathway	ISO

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway

non-canonical Wnt signaling pathway

Wnt signaling pathway, calcium modulating pathway

canonical Wnt signaling pathway

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [inference]

G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

cell development [inference]

neuron development [inference]

inner ear receptor cell development

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of smell

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

cochlea morphogenesis

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

muscular septum morphogenesis

cardiac septum morphogenesis [inference]

ventricular septum morphogenesis

anatomical structure development [inference]

cell development [inference]

neuron development [inference]

inner ear receptor cell development

animal gross anatomical part developmental process [inference]

hard palate development

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

cell development [inference]

neuron development [inference]

inner ear receptor cell development

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway

non-canonical Wnt signaling pathway

Wnt signaling pathway, calcium modulating pathway

canonical Wnt signaling pathway

G protein-coupled receptor signaling pathway [inference]

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [inference]

G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IEA
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane

plasma membrane

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IEA
G protein-coupled receptor activity
protein binding	IPI
Wnt-protein binding	IBA
PDZ domain binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

Wnt-protein binding

protein domain specific binding [inference]

PDZ domain binding

identical protein binding

protein dimerization activity [inference]

protein heterodimerization activity

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	2535	HGNC:4040
Rattus norvegicus	64512	RGD:71012
Caenorhabditis elegans	172856	WB:WBGene00003397
Caenorhabditis elegans	178768	WB:WBGene00000478
Drosophila melanogaster	45307	FB:FBgn0001085