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mannosyl-oligosaccharide glucosidase

Summary

Gene Symbol

Mogs

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

57377

PubChem

57377

Alliance of Genome Resources

MGI:1929872

Annotation

Keyword

3D-structure
Endoplasmic reticulum
Glycoprotein
Glycosidase
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q80UM7	Endoplasmic reticulum alpha-glucosidase I Glucosidase 1 Glycoprotein-processing glucosidase I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
oligosaccharide metabolic process	IEA
protein N-linked glycosylation	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IBA IEA
endoplasmic reticulum	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying 1 entry
GO Term	Evidence Code	PMID
Glc3Man9GlcNAc2 oligosaccharide glucosidase activity	IBA IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

glucosidase activity [inference]

Glc3Man9GlcNAc2 oligosaccharide glucosidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Glycosyl hydrolase family 63, N-terminal

Functional Category

H: Coenzyme transport and metabolism
J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis

Displaying **all 4** entries
Gene Ontology
Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity
protein N-linked glycosylation

Displaying **all 6** entries
InterPro
Glycoside hydrolase family 63
Glycosyl hydrolase family 63, C-terminal
Glycosyl hydrolase family 63, N-terminal domain superfamily
Glycosyl hydrolase family 63, N-terminal
Six-hairpin glycosidase superfamily
Six-hairpin glycosidase-like superfamily

Rhea

H₂O

β-D-glucose

Enzyme

3.2.1.106

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0070254	congenital disorder of glycosylation type IIb	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 70** of **120** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Propithecus coquereli	105821480			PROCO29683
Microcebus murinus	105884584			MICMU11107
Dipodomys ordii	105999585	10020_0:0044a1		DIPOR19724
Salmo salar	106602766			SALSA120719
Salmo salar	106609973			SALSA137705
Equus asinus asinus	106823842			EQUAS25713
Marmota marmota marmota	107154218	9994_0:003839
Sinocyclocheilus grahami	107551727			SINGR02093
Sinocyclocheilus grahami	107567052			SINGR83000
Ictalurus punctatus	108260492			ICTPU24137

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024