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Summary

Gene Symbol

futsch

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

5740544

PubChem

5740544

Alliance of Genome Resources

FB:FBgn0259108

Annotation

Keyword

Coiled coil
Cytoskeleton
Developmental protein
Microtubule
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9W596	MAP1B homolog
M9NGG5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
regulation of synaptic assembly at neuromuscular junction	IMP	10839356 15269269 31156389
microtubule cytoskeleton organization	IBA IEA IMP	10839356 25429138 31156389
positive regulation of axon regeneration	IMP	31919191
olfactory learning	IMP	15772149
dendrite morphogenesis	IMP	10839355

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

microtubule-based movement [inference]

transport along microtubule [inference]

axo-dendritic transport

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization [inference]

neurofilament cytoskeleton organization

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

intermediate filament cytoskeleton organization [inference]

neurofilament cytoskeleton organization

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

dendrite development

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

olfactory learning

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

olfactory learning

chemosensory behavior [inference]

olfactory behavior [inference]

olfactory learning

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

anatomical structure development [inference]

dendrite development

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to wounding [inference]

positive regulation of axon regeneration

positive regulation of developmental process [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of axon regeneration

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to wounding [inference]

positive regulation of axon regeneration

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of response to wounding [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of response to wounding [inference]

positive regulation of axon regeneration

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction

positive regulation of developmental process [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

regulation of microtubule depolymerization

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of neuron apoptotic process [inference]

negative regulation of neuron apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of neuron apoptotic process

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of microtubule cytoskeleton organization [inference]

regulation of microtubule polymerization or depolymerization [inference]

regulation of microtubule depolymerization

regulation of protein-containing complex disassembly [inference]

regulation of protein depolymerization [inference]

regulation of microtubule depolymerization

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of neuromuscular junction development [inference]

regulation of synaptic assembly at neuromuscular junction

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction

regulation of supramolecular fiber organization [inference]

regulation of microtubule depolymerization

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

positive regulation of axon regeneration

positive regulation of neuron projection regeneration [inference]

positive regulation of axon regeneration

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
microtubule	IBA IEA
microtubule associated complex	IBA IDA	10839355 10839356
neuronal cell body	IBA IDA	17646657
neuromuscular junction	IMP	31156389
dendrite	IBA IDA	17646657

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex

cellular anatomical entity [inference]

cytosol

cell junction [inference]

synapse

neuromuscular junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

cell body [inference]

neuronal cell body

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 4** entries
GO Term	Evidence Code	PMID
kinase binding	IPI	21159966
protein binding	IPI	11733059
actin binding	IBA
microtubule binding	IBA IDA IEA	10839355 10839356

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding

tubulin binding [inference]

microtubule binding

enzyme binding [inference]

kinase binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

microtubule-associated protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
actin binding
dendrite development
microtubule binding
microtubule cytoskeleton organization
regulation of microtubule depolymerization

Displaying 1 entry
InterPro
Microtubule associated protein 1

Alliance of Genome Resources

Expression

Displaying **all 6** entries
Location	References
microtubule associated complex	PMID:10839355 PMID:10839356
neuronal cell body	PMID:10839355 PMID:17646657
axon	PMID:10839355 PMID:17646657
dendrite	PMID:10839355 PMID:17646657
membrane	FB:FBrf0231198
microtubule cytoskeleton	PMID:10839355

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:0050454	periventricular nodular heterotopia	Alliance of Genome Resources
DOID:0050564	autosomal dominant nonsyndromic deafness	Alliance of Genome Resources
DOID:11832	visual epilepsy	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 53 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Drosophila persimilis	6596730	7234_1:002578
Drosophila sechellia	6615983	7238_1:003471
Drosophila virilis	6635475	7244_1:0033d1
Drosophila willistoni	6644861	7260_0:001939
Drosophila simulans	6724865	7240_1:002ea1
Danio rerio	100151220		ZFIN:ZDB-GENE-100426-2
Drosophila suzukii	108016595	28584_0:002062
Drosophila biarmipes	108023190	125945_0:0028b4
Drosophila rhopaloa	108042832	1041015_1:0031bd
Drosophila takahashii	108058400	29030_0:000515

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements