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ATP binding cassette subfamily G member 2

Summary

Gene Symbol

ABCG2

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 574307
PubChem: 574307

Annotation

Keyword

ATP-binding
Cell membrane
Disulfide bond
Glycoprotein
Lipid transport
Mitochondrion
Phosphoprotein
Reference proteome
Translocase
Transmembrane helix
Transport

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q5MB13	ATP-binding cassette sub-family G member 2 Urate exporter
H9EWM4	ATP-binding cassette sub-family G member 2 Urate exporter
I2CY94	ATP-binding cassette sub-family G member 2 Urate exporter
G8F1F3	ATP-binding cassette sub-family G member 2 Urate exporter

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
lipid transport
biotin transport
riboflavin transport
transmembrane transport
renal urate salt excretion

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

multicellular organismal process [inference]

system process [inference]

renal system process [inference]

renal tubular secretion [inference]

renal urate salt excretion

excretion [inference]

renal tubular secretion [inference]

renal urate salt excretion

localization [inference]

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

transmembrane transport

organic substance transport [inference]

lipid transport

organic anion transport [inference]

riboflavin transport

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

biotin transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

biotin transport

nitrogen compound transport [inference]

riboflavin transport

amide transport [inference]

biotin transport

sulfur compound transport [inference]

biotin transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
apical plasma membrane
brush border membrane
mitochondrial membrane
membrane raft

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

mitochondrial membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

membrane microdomain [inference]

membrane raft

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA	22301074
ABC-type xenobiotic transporter activity
urate transmembrane transporter activity
biotin transmembrane transporter activity
efflux transmembrane transporter activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

biotin transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

riboflavin transmembrane transporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

biotin transmembrane transporter activity

efflux transmembrane transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

amide transmembrane transporter activity [inference]

biotin transmembrane transporter activity

xenobiotic transmembrane transporter activity [inference]

ABC-type xenobiotic transporter activity

vitamin transmembrane transporter activity [inference]

sulfur compound transmembrane transporter activity [inference]

biotin transmembrane transporter activity

salt transmembrane transporter activity [inference]

binding [inference]

protein binding [inference]

protein dimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity

ABC-type transporter activity

ABC-type xenobiotic transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-binding cassette sub-family G member

Functional Category

C: Energy production and conversion
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 5** entries
InterPro
AAA+ ATPase domain
ABC transporter family G domain
ABC transporter-like, ATP-binding domain
ABC-2 type transporter, transmembrane domain
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **1 - 10** of 58 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	9429	HUMAN76514
Mus musculus	26357	MOUSE49634
Rattus norvegicus	312382	RATNO29675
Sus scrofa	397073	PIGXX34445
Pan troglodytes	471251	PANTR34094
Canis lupus familiaris	478472	CANLF13058
Bos taurus	536203	BOVIN31248
Danio rerio	735312	DANRE24011
Ovis aries	780508	SHEEP17242
Oryctolagus cuniculus	100008640	RABIT05237

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OrthoDB (Group)

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