GlyCosmos Portal

Submissions

secreted frizzled related protein 4

Summary

Gene Symbol

SFRP4

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 574393
PubChem: 574393

Annotation

Keyword

Developmental protein
Differentiation
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7YRN1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
negative regulation of cell population proliferation
cell differentiation
regulation of BMP signaling pathway
non-canonical Wnt signaling pathway	IEA	30032202
canonical Wnt signaling pathway	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

cellular developmental process [inference]

cell differentiation

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

bone morphogenesis

cellular developmental process [inference]

cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

negative regulation of non-canonical Wnt signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

negative regulation of non-canonical Wnt signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

negative regulation of non-canonical Wnt signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IEA	30032202
cytoplasm	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
Wnt-protein binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

Wnt-protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

frizzled

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
Wnt-protein binding
canonical Wnt signaling pathway
cell differentiation
non-canonical Wnt signaling pathway

Displaying **all 6** entries
InterPro
Frizzled cysteine-rich domain superfamily
Frizzled domain
Frizzled/secreted frizzled-related protein
Netrin domain
Netrin module, non-TIMP type
Tissue inhibitor of metalloproteinases-like, OB-fold