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polypeptide N-acetylgalactosaminyltransferase 16

Summary

Gene Symbol

GALNT16

Aliases

GalNAc-T16
KIAA1130
polypeptide GalNAc transferase 16

Organism

Homo sapiens (human)

External Links

NCBI Gene

57452

GGDB ID

gg212

HGNC

23233

mRNA

NM_020692.2

map

14q24.1

Protein

NP_065743.2

OMIM

615132

KEGG Gene ID

hsa:57452

PubChem

57452

Alliance of Genome Resources

HGNC:23233

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycosyltransferase
Golgi apparatus
Lectin
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8N428	Polypeptide GalNAc transferase 16 Polypeptide GalNAc transferase-like protein 1 Polypeptide N-acetylgalactosaminyltransferase-like protein 1 Protein-UDP acetylgalactosaminyltransferase-like protein 1 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 1
Q68VJ8	Protein-UDP acetylgalactosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein O-linked glycosylation	IBA
protein O-linked glycosylation via threonine	IDA	22186971
protein O-linked glycosylation via serine	IDA	22186971

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

peptidyl-threonine modification [inference]

protein O-linked glycosylation via threonine

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi apparatus	IBA
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
carbohydrate binding	IEA
polypeptide N-acetylgalactosaminyltransferase activity	IBA IDA	22186971

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

hexosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

catalytic activity, acting on a protein [inference]

polypeptide N-acetylgalactosaminyltransferase activity

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000100626

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg212

Gene Symbol

GALNT16

KEGG BRITE Database

Orthology

K00710

Name

polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]

References

9295285

Rhea

RHEA:23956

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

RHEA:52424

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0060250	idiopathic scoliosis	DisGeNET
DOID:1612	breast cancer	DisGeNET DisGeNET DisGeNET DisGeNET
DOID:3459	breast carcinoma	DisGeNET DisGeNET

Ortholog

Displaying entries **1 - 10** of 80 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	180302	WB:WBGene00001629
Drosophila melanogaster	43394	FB:FBgn0039596
Callorhinchus milii	103178463		CALMI15756
Danio rerio	799387	ZFIN:ZDB-GENE-131120-189	DANRE12086
Astyanax mexicanus	103044537		ASTMX09499
Electrophorus electricus	113567750		ELEEL48806
Esox lucius	105015901		ESOLU44516
Salmo trutta	115161837		SALTR56814
Salmo trutta	115181901		SALTR56814
Gadus morhua	115544064		GADMO48067

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Tools

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Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements